Autism, youth suicide, and psychedelics: A review of the 21st century evidence

MH Chen, TP Su, JW Hsu, SJ Tsai - Journal of the Chinese …, 2024 - journals.lww.com
The concurrent rise in the prevalence of autism and youth suicide has drawn public health
and professional attention. The renaissance of psychedelics in psychiatry occurred in the …

Whole-genome sequencing analysis of suicide deaths integrating brain-regulatory eQTLs data to identify risk loci and genes

S Han, E DiBlasi, ET Monson, A Shabalin, E Ferris… - Molecular …, 2023 - nature.com
Recent large-scale genome-wide association studies (GWAS) have started to identify
potential genetic risk loci associated with risk of suicide; however, a large portion of suicide …

Transdiagnostic behavioral and genetic contributors to repetitive negative thinking: a machine learning approach

KL Forthman, R Kuplicki, H Yeh, SS Khalsa… - Journal of psychiatric …, 2023 - Elsevier
Background Repetitive negative thinking (RNT) is a symptom that can negatively impact the
treatment and course of common psychiatric disorders such as depression and anxiety. We …

Large epigenome-wide association study identifies multiple novel differentially methylated CpG sites associated with suicidal thoughts and behaviors in veterans

NA Kimbrel, ME Garrett, MK Evans, C Mellows… - Frontiers in …, 2023 - frontiersin.org
Introduction The US suicide mortality rate has steadily increased during the past two
decades, particularly among military veterans; however, the epigenetic basis of suicidal …

Gut microbiota and Alzheimer's disease: Exploring natural product intervention and the Gut–Brain axis for therapeutic strategies

JK Pasupalak, P Rajput, GL Gupta - European Journal of Pharmacology, 2024 - Elsevier
Numerous studies conducted over the last ten years have shown a strong correlation
between the gut microbiota and the onset and progression of Alzheimer's disease (AD) …

Genome-wide methylome-based molecular pathologies associated with depression and suicide

Y Dwivedi, B Roy, PK Korla - Neuropsychopharmacology, 2024 - nature.com
Major depressive disorder (MDD) is a debilitating disorder. Suicide attempts are 5-times
higher in MDD patients than in the general population. Interestingly, not all MDD patients …

Brain and blood transcriptome profiles delineate common genetic pathways across suicidal ideation and suicide

S Sun, Q Liu, Z Wang, Y Huang, ME Sublette… - Molecular …, 2024 - nature.com
Human genetic studies indicate that suicidal ideation and behavior are both heritable. Most
studies have examined associations between aberrant gene expression and suicide …

Identification of novel targets and pathways to distinguish suicide dependent or independent on depression diagnosis

S Peng, Y Zhou, L Xiong, Q Wang - Scientific reports, 2023 - nature.com
In recent years, postmortem brain studies have revealed that some molecular, cellular, and
circuit changes associated with suicide, have an independent or additive effect on …

New insights into suicidal behavior from large multi-ancestry genetic meta-analysis

EB Binder - American journal of psychiatry, 2023 - Am Psychiatric Assoc
Suicide is the second leading cause of death among 15-to 29-year-olds (1), and a history of
psychiatric disorders is one of the main risk factors. Hence, understanding the causes of and …

Identification of blood transcriptome modules associated with suicidal ideation in patients with major depressive disorder

M Wang, H Xiang, J Wei, Y Dou, Y Yan, Y Du, H Fan… - Scientific Reports, 2025 - nature.com
The risk of suicide in patients with major depressive disorder (MDD) poses a major concern,
with studies suggesting that genetics may be a contributing factor. Although there are many …