Bringing aptamers into technologies: Impact of spacer terminations
We propose a low cost modeling approach to screen the impact of aptamer structural
modifications on their biomechanical stability. This responds to the current immature control …
modifications on their biomechanical stability. This responds to the current immature control …
Atomic scale determination of enzyme flexibility and active site stability through static modes: case of dihydrofolate reductase
A Static Mode approach is used to screen the biomechanical properties of DHFR. In this
approach, a specific external stimulus may be designed at the atomic scale granularity to …
approach, a specific external stimulus may be designed at the atomic scale granularity to …
Toward in silico biomolecular manipulation through static modes: atomic scale characterization of HIV-1 protease flexibility
Probing biomolecular flexibility with atomic-scale resolution is a challenging task in current
computational biology for fundamental understanding and prediction of biomolecular …
computational biology for fundamental understanding and prediction of biomolecular …
[PDF][PDF] Mimicking DNA stretching with the Static Mode method: Shear stress versus transverse pulling stress
DNA sequencing using nanopores is closer than ever to become a reality, but further
research and development still need to be done, especially to unravel the atomic-scale …
research and development still need to be done, especially to unravel the atomic-scale …