Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …

Stress often affects our social lives. When undergoing high-level or persistent stress,
individuals frequently retract from social interactions and become irritable and hostile …

The chronic mild stress (CMS) model of depression has high validity but has in the past
been criticized for being difficult to replicate. However, a large number of recent publications …

Animals housed in artificial habitats are confronted by a wide range of potentially
provocative environmental challenges. In this article, we review many of the potential …

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field calls …

The widely accepted stress-diathesis hypothesis of depression postulates that genetic
factors contribute to biological vulnerability. Based on this concept, the unpredictable …

Effects of unpredictable chronic mild stress (UCMS) on anhedonic-like behaviour, physical
state, body weight, learning and memory were investigated in three strains of mice. These …

Fleas are one of the most interesting and fascinating taxa of ectoparasites. All species in this
relatively small order are obligatory haematophagous (blood-feeding) parasites of higher …

Over the years, it has become increasingly clear that males and females respond differently
towards environmental stressors, highlighting the importance of including both sexes when …

Chronic stress is increasingly considered to be a main risk factor for the development of a
variety of psychiatric diseases such as depression. This is further supported by an impaired …