Bioinspired out-of-equilibrium systems will set the scene for the next generation of molecular
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …

Research of a past decade and a half leaves no doubt that complete understanding of
protein functionality requires close consideration of the fact that many functional proteins do …

Mammalian oocytes go through a long and complex developmental process while acquiring
the competencies that are required for fertilization and embryogenesis. Recent advances in …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

During mitosis, transcription is shut off, chromatin condenses, and most transcription factors
(TFs) are reported to be excluded from chromosomes. How do daughter cells re-establish …

The specificity of cellular responses to receptor stimulation is encoded by the spatial and
temporal dynamics of downstream signalling networks. Temporal dynamics are coupled to …

The microtubules that comprise mitotic spindles in animal cells are nucleated at
centrosomes and by spindle assembly factors that are activated in the vicinity of chromatin …

Life depends on cell proliferation and the accurate segregation of chromosomes, which are
mediated by the microtubule (MT)-based mitotic spindle and∼ 200 essential MT-associated …

In the bacterium Escherichia coli, the Min proteins oscillate between the cell poles to select
the cell center as division site. This dynamic pattern has been proposed to arise by self …

Chromosome segregation in mammalian oocytes is driven by a microtubule spindle lacking
centrosomes. Here, we analyze centrosome-independent spindle assembly by quantitative …