Flavonoids: classification, function, and molecular mechanisms involved in bone remodelling

P Ramesh, R Jagadeesan, S Sekaran… - Frontiers in …, 2021 - frontiersin.org
Flavonoids are polyphenolic compounds spotted in various fruits, vegetables, barks, tea
plants, and stems and many more natural commodities. They have a multitude of …

The effect of icariin on bone metabolism and its potential clinical application

Z Wang, D Wang, D Yang, W Zhen, J Zhang… - Osteoporosis …, 2018 - Springer
Osteoporosis is a bone disease characterized by reduced bone mass, which leads to
increased risk of bone fractures, and poses a significant risk to public health, especially in …

Pharmacological effects of icariin

C He, Z Wang, J Shi - Advances in pharmacology, 2020 - Elsevier
Icariin (ICA) is a principal active component from traditional Chinese medicine Epimedium
grandiflorum. To explain its traditional medical usages by modern science, a variety of …

Traditional Chinese medicine formulas for the treatment of osteoporosis: implication for antiosteoporotic drug discovery

ND Zhang, T Han, BK Huang, K Rahman… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Osteoporosis is a chronic epidemic which can leads to
enhanced bone fragility and consequent an increase in fracture risk. Traditional Chinese …

Intracellular signaling pathways of inflammation modulated by dietary flavonoids: The most recent evidence

L Chen, H Teng, Z Jia, M Battino, A Miron… - Critical reviews in …, 2018 - Taylor & Francis
Dietary flavonoids, which occur in many plant foods, are considered as the most active
constituents among the plant-derived ones in vitro and in vivo. To date, many studies have …

Pharmacological effects and pharmacokinetic properties of icariin, the major bioactive component in Herba Epimedii

C Li, Q Li, Q Mei, T Lu - Life Sciences, 2015 - Elsevier
Herba Epimedii is an important medicinal plant which has been used in various traditional
Chinese formulations for thousands of years as well as in modern proprietary traditional …

Phytochemistry and pharmacology of natural prenylated flavonoids

HW Lv, QL Wang, M Luo, MD Zhu, HM Liang… - Archives of Pharmacal …, 2023 - Springer
Prenylated flavonoids are a special kind of flavonoid derivative possessing one or more
prenyl groups in the parent nucleus of the flavonoid. The presence of the prenyl side chain …

[PDF][PDF] Pharmacological agents and natural compounds: available treatments for osteoporosis.

M Martiniakova, M Babikova, R Omelka - Journal of Physiology & …, 2020 - jpp.krakow.pl
Osteoporosis, a systemic skeletal disease characterized by a decrease in bone mass and
deterioration of bone structure leading to an increased risk of fragility fractures, represents …

Therapeutic anabolic and anticatabolic benefits of natural Chinese medicines for the treatment of osteoporosis

J He, X Li, Z Wang, S Bennett, K Chen, Z Xiao… - Frontiers in …, 2019 - frontiersin.org
Osteoporosis is a bone disease characterized by increasing osseous fragility and fracture
due to the reduced bone mass and microstructural degradation. Primary pharmacological …

Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling

LG Ming, KM Chen, CJ Xian - Journal of cellular physiology, 2013 - Wiley Online Library
Increasingly natural products particularly flavonoids are being explored for their therapeutic
potentials in reducing bone loss and maintaining bone health. This study has reviewed …