Progress in Pharmacometrics Implementation and Regulatory Integration in Africa: A Systematic Review

BS Ndzamba, S Egieyeh… - Clinical Pharmacology & …, 2024 - Wiley Online Library
The availability of clinical trial data, advocacy, and increased funding has facilitated the
implementation of pharmacometrics in Africa, resulting in the establishment of additional …

[HTML][HTML] Systemic delivery of bictegravir and tenofovir alafenamide using dissolving microneedles for HIV preexposure prophylaxis

C Zhang, Y Wu, ARJ Hutton, AHB Sabri… - International Journal of …, 2024 - Elsevier
Human immunodeficiency virus (HIV) continues to pose a serious threat to global health.
Oral preexposure prophylaxis (PrEP), considered highly effective for HIV prevention, is the …

[HTML][HTML] Pharmacogenetics of tenofovir drug transporters in the context of HBV: Is there an impact?

J Cusato, A Manca, A Palermiti, J Mula… - Biomedicine & …, 2024 - Elsevier
Background Current treatments for chronic hepatitis B management include orally
administered nucleos (t) ide analogues, such as tenofovir (TDF), which is an acyclic adenine …

Pharmacokinetics of tenofovir alafenamide, emtricitabine, and dolutegravir in a patient on peritoneal dialysis

SA Massih, MG Atta, CL Thio, JA Tornheim… - AIDS research and …, 2024 - Springer
Introduction Peritoneal dialysis (PD) is an effective renal replacement modality in people
with HIV (PWH) with end-stage kidney disease (ESKD), particularly those with residual …

Progress in Pharmacometrics Implementation and Regulatory Integration in Africa: A Systematic Review

NB S'fiso, E Samuel, F Pius - 2024 - uwcscholar.uwc.ac.za
The availability of clinical trial data, advocacy, and increased funding has facilitated the
implementation of pharmacometrics in Africa, resulting in the establishment of additional …

Central Nervous System Antiviral Pharmacology

SN Avedissian - 2024 - digitalcommons.unmc.edu
Soon after viral infection, viruses like Human Immunodeficiency Virus (HIV) and SARS-CoV-
2 can disseminate throughout the body and establish reservoirs in the central nervous …

[PDF][PDF] Development and application of novel dried blood spot methods for the quantification of antiretroviral drugs and their metabolites

B Thompson - 2024 - livrepository.liverpool.ac.uk
Background-Patient adherence to their antiretroviral (ARV) drug regimen is vital in achieving
successful treatment ie, viral suppression. The benefits of dried blood spots (DBS) as an …