Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …

In this narrative review, the biological/biochemical impact (toxicity) of a large array of known
individual uremic retention solutes and groups of solutes is summarized. We classified these …

Ghrelin, a gastric-derived acylated peptide, regulates energy homeostasis by transmitting
information about peripheral nutritional status to the brain, and is essential for protecting …

Objective Complex local crosstalk amongst endocrine cells within the islet ensures tight
coordination of their endocrine output. This is illustrated by the recent demonstration that the …

The a 28-amino acid peptide ghrelin was discovered in 1999 as a growth hormone (GH)
releasing peptide. Soon after its discovery, ghrelin was found to increase body weight and …

Ghrelin is a hormone that stimulates growth hormone secretion and signals energy
insufficiency via interaction with its receptor, the growth hormone secretagogue receptor …

The peptide hormone ghrelin is the only known protein modified with an O-linked octanoyl
side group, which occurs on its third serine residue. This modification is crucial for ghrelin's …

The gastrointestinal tract has a crucial role in the control of energy homeostasis through its
role in the digestion, absorption, and assimilation of ingested nutrients. Furthermore, signals …

Ghrelin, an acylated upper gastrointestinal peptide, is the only known orexigenic hormone.
Considerable evidence implicates ghrelin in mealtime hunger and meal initiation …

Ghrelin is the endogenous ligand for the growth hormone secretagogue receptor (GHSR;
ghrelin receptor). Since its discovery, accumulating evidence has suggested that ghrelin …