Once a rarely used subset of medical treatments, protein therapeutics have increased
dramatically in number and frequency of use since the introduction of the first recombinant …

Purpose—Our goal is to provide an overview of the current evidence about components of
the evaluation and treatment of adults with acute ischemic stroke. The intended audience is …

The term acute coronary syndrome (ACS) refers to any group of clinical symptoms
compatible with acute myocardial ischemia and includes unstable angina (UA), non—ST …

Background A substantial proportion of patients receiving fibrinolytic therapy for myocardial
infarction with ST-segment elevation have inadequate reperfusion or reocclusion of the …

ContextRapid time to treatment with thrombolytic therapy is associated with lower mortality in
patients with acute myocardial infarction (MI). However, data on time to primary angioplasty …

The management of acute myocardial infarction continues to undergo major changes. Good
practice should be based on sound evidence derived from well-conducted clinical trials …

Background—In the setting of an acute coronary syndrome (ACS), anemia has the potential
to worsen myocardial ischemia; however, data relating anemia to clinical outcomes in ACS …

The ACC/AHA Task Force on Practice Guidelines was formed to gather information and
make recommendations about appropriate use of technology for the diagnosis and …

Background—Use of abciximab in combination with administration of thrombolytics has
been shown to improve epicardial and microvascular coronary blood flow in acute …

Background We hypothesized that percutaneous coronary intervention (PCI) preceded by
early treatment with abciximab plus half-dose reteplase (combination-facilitated PCI) or with …