Rat models of spinal cord injury: from pathology to potential therapies

J Kjell, L Olson - Disease models & mechanisms, 2016 - journals.biologists.com
ABSTRACT A long-standing goal of spinal cord injury research is to develop effective spinal
cord repair strategies for the clinic. Rat models of spinal cord injury provide an important …

Oxidative stress and schizophrenia: recent breakthroughs from an old story

FE Emiliani, TW Sedlak, A Sawa - Current opinion in psychiatry, 2014 - journals.lww.com
These advances have made this topic of paramount importance to the understanding of
schizophrenia and will play a role in advancing the treatment options. This review covers …

Are we getting closer to valid translational models for major depression?

O Berton, CG Hahn, ME Thase - Science, 2012 - science.org
Advances in characterizing the neuropathology and functional dysconnectivity of depression
and promising trials with emerging circuit-targeted and fast-onset therapeutics are providing …

Scents and nonsense: olfactory dysfunction in schizophrenia

BI Turetsky, CG Hahn, K Borgmann-Winter… - Schizophrenia …, 2009 - academic.oup.com
Among the sensory modalities, olfaction is most closely associated with the frontal and
temporal brain regions that are implicated in schizophrenia and most intimately related to …

Translational potential of olfactory mucosa for the study of neuropsychiatric illness

K Borgmann-Winter, SL Willard, D Sinclair… - Translational …, 2015 - nature.com
The olfactory mucosa (OM) is a unique source of regenerative neural tissue that is readily
obtainable from living human subjects and thus affords opportunities for the study of …

Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium

ES Tucker, MK Lehtinen, T Maynard… - …, 2010 - journals.biologists.com
Neural precursors in the developing olfactory epithelium (OE) give rise to three major
neuronal classes–olfactory receptor (ORNs), vomeronasal (VRNs) and gonadotropin …

A non-invasive method to isolate the neuronal linage from the nasal epithelium from schizophrenic and bipolar diseases

G Benítez-King, A Riquelme, L Ortíz-López… - Journal of neuroscience …, 2011 - Elsevier
Brain imaging and histopathological studies suggest that neurodevelopmental anomalies
play a key role in the etiology of schizophrenia (SZ) and bipolar disorder (BD). New neuron …

The olfactory deficits of depressed patients are restored after remission with venlafaxine treatment

R Colle, K El Asmar, C Verstuyft, PM Lledo… - Psychological …, 2022 - cambridge.org
BackgroundIt is unclear whether olfactory deficits improve after remission in depressed
patients. Therefore, we aimed to assess in drug-free patients the olfactory performance of …

Unraveling the Link between Olfactory Deficits and Neuropsychiatric Disorders

K Yang, C Ayala-Grosso, JP Bhattarai… - Journal of …, 2023 - Soc Neuroscience
Smell loss has caught public attention during the recent COVID-19 pandemic. Research on
olfactory function in health and disease gains new momentum. Smell deficits have long …

Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells

L Galindo, E Moreno, F López-Armenta, D Guinart… - Molecular …, 2018 - Springer
Abstract Cannabinoid CB1 receptors (CB 1 R) and serotonergic 2A receptors (5HT 2A R)
form heteromers in the brain of mice where they mediate the cognitive deficits produced by …