Friedreich's ataxia (FA)(OMIM# 229300) is the most frequent inherited ataxia worldwide and
a devastating multisystemic disease [1]. FA usually presents in adolescence with a slowly …

Friedreich Ataxia (FRDA) is an inherited neuromuscular disorder triggered by a deficit of the
mitochondrial protein frataxin. At a cellular level, frataxin deficiency results in insufficient iron …

Friedreich's ataxia (FRDA) is a severe multisystemic disorder caused by a deficiency of the
mitochondrial protein frataxin. While some aspects of FRDA pathology are developmental …

Background Early studies in cellular models suggested an iron accumulation in Friedreich's
ataxia (FA), yet findings from patients are lacking. Objectives The objective is to characterize …

Friedreich ataxia (FRDA) is the most common inherited ataxia, primarily impacting the
nervous system and the heart. It is characterized by GAA repeat expansion in the FXN gene …

Nearly half of all adults in the United States are currently living with some form of
cardiovascular disease. In many cases this progresses to heart failure, for which there is no …

The binary model of existence consists of health and disease, with health being complete
physical, mental, and social well-being and disease being a pathological process. Humanity …