Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Vaccines based on historical virus isolates provide limited protection from continuously
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …

Current yearly seasonal influenza vaccines primarily induce an antibody response directed
against the immunodominant but continually diversifying hemagglutinin (HA) head region …

There is growing appreciation for neuraminidase (NA) as an influenza vaccine target;
however, its antigenicity remains poorly characterized. In this study, we isolated three …

Background The development of a universal influenza virus vaccine, to protect against both
seasonal and pandemic influenza A viruses, is a long-standing public health goal. The …

Highly contagious respiratory illnesses like influenza and COVID-19 pose serious risks to
public health. A two-in-one vaccine would be ideal to avoid multiple vaccinations for these …

The influenza A virus (IAV) is a ubiquitous and continuously evolving respiratory pathogen.
The intranasal vaccination mimicking natural infections is an attractive strategy for …

Broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin (HA) stem of influenza
A viruses (IAVs) tend to be effective against either group 1 or group 2 viral diversity. In rarer …

Seasonal influenza vaccines typically provide strain‐specific protection and are
reformulated annually, which is a complex and time‐consuming process. Multiepitope …

Zoonotic transmission of H5N1 highly pathogenic avian influenza virus (HPAIV) into the
human population is an increasing global threat. The recent 2022 HPAIV outbreak …