HIV genetic diversity and drug resistance
AF Santos, MA Soares - Viruses, 2010 - mdpi.com
Most of the current knowledge on antiretroviral (ARV) drug development and resistance is
based on the study of subtype B of HIV-1, which only accounts for 10% of the worldwide HIV …
based on the study of subtype B of HIV-1, which only accounts for 10% of the worldwide HIV …
Surveillance of HIV transmitted drug resistance in Latin America and the Caribbean: a systematic review and meta-analysis
Background HIV transmitted drug resistance (TDR) remains at moderate level in Latin
America and the Caribbean (LAC). However, different epidemiologic scenarios could …
America and the Caribbean (LAC). However, different epidemiologic scenarios could …
Brazilian Network for HIV Drug Resistance Surveillance: a survey of individuals recently diagnosed with HIV
LA Inocencio, AA Pereira, MCA Sucupira… - Journal of the …, 2009 - Springer
Use of antiretrovirals is widespread in Brazil, where more than 200,000 individuals are
under treatment. Although general prevalence of primary antiretroviral resistance in Brazil is …
under treatment. Although general prevalence of primary antiretroviral resistance in Brazil is …
Origin and evolutionary history of HIV-1 subtype C in Brazil
Objective: To investigate the origin and to reconstruct the onset date of the HIV-1 subtype C
epidemic in Brazil. Design: Three independent datasets of subtype C sequences isolated …
epidemic in Brazil. Design: Three independent datasets of subtype C sequences isolated …
[HTML][HTML] The increasing prevalence of HIV-1 subtype C in Southern Brazil and its dispersion through the continent
The HIV-1 has evolved swiftly and the scenario of HIV-1 genetic diversity is constantly
changing. In South America, recombinant forms of subtypes B, F1, and BF1 have historically …
changing. In South America, recombinant forms of subtypes B, F1, and BF1 have historically …
The HIV-1 subtype C epidemic in South America is linked to the United Kingdom
Background The global spread of HIV-1 has been accompanied by the emergence of
genetically distinct viral strains. Over the past two decades subtype C viruses, which …
genetically distinct viral strains. Over the past two decades subtype C viruses, which …
HIV genotypes and primary drug resistance among HIV-seropositive blood donors in Brazil: role of infected blood donors as sentinel populations for molecular …
CS Alencar, EC Sabino, SMF Carvalho… - JAIDS Journal of …, 2013 - journals.lww.com
Background: There are few surveillance studies analyzing genotypes or primary
(transmitted) drug resistance in HIV-infected blood donors in Brazil. The aim of this study …
(transmitted) drug resistance in HIV-infected blood donors in Brazil. The aim of this study …
Primary antiretroviral drug resistance among HIV type 1-infected individuals in Brazil
Infection with drug-resistant human immunodeficiency virus type 1 (HIV-1) has been
documented in all countries that have surveyed for it and may result in an unfavorable …
documented in all countries that have surveyed for it and may result in an unfavorable …
High-resolution phylogenetics and phylogeography of human immunodeficiency virus type 1 subtype C epidemic in South America
NMC Véras, RR Gray… - Journal of general …, 2011 - microbiologyresearch.org
Human immunodeficiency virus type 1 subtype C (HIV-1C) represents 30–65% of HIV
infections in southern Brazil, and isolated cases of HIV-1C infection have also been reported …
infections in southern Brazil, and isolated cases of HIV-1C infection have also been reported …
Comprehensive characterization of HIV-1 molecular epidemiology and demographic history in the Brazilian region most heavily affected by AIDS
T Gräf, H Machado Fritsch, RM de Medeiros… - Journal of …, 2016 - Am Soc Microbiol
The high incidence of AIDS cases and the dominance of HIV-1 subtype C infections are two
features that distinguish the HIV-1 epidemic in the two southernmost Brazilian states (Rio …
features that distinguish the HIV-1 epidemic in the two southernmost Brazilian states (Rio …