Inflammatory bowel disease (IBD) is a chronic inflammatory disease with a high prevalence
and canceration rate. The immune disorder is one of the recognized mechanisms …

Aim This study evaluated the immunomodulatory and delivery potential of adipose tissue-
isolated MSC-derived exosomes as a prophylactic regimen through a sublingual route in the …

Due to their immunomodulatory capacities, mesenchymal stem cells (MSCs) have been
extensively used as therapeutic approaches in cell-based therapy for various inflammatory …

Relaxin-2 exerts many favourable cardiovascular effects in pathological circumstances such
as atrial fibrillation (AF) and heart failure, but the mechanisms underlying its actions are not …

Background Lichen planus (LP) is a chronic autoimmune disease with different clinical
subtypes including cutaneous LP (CLP) and oral LP (OLP). We aimed to compare mRNA …

Increasing the efficacy of allergen-specific intranasal immunotherapy (INIT) has recently
been the main goal of several studies to establish this route as a safe delivery method …

BACKGROUND Colorectal cancer is a complex disease with high mortality rates. Over time,
the treatment of metastatic colorectal cancer (mCRC) has gradually improved due to the …

Abstract T helper (Th)-17 cells are a distinct and important subset of Th cells and their
functions are due to the ability of production and secretion of key cytokines in the immune …

Allergen-specific immunotherapy (AIT) can alter the natural course of an allergic disease. It
is widely held that the efficacy of a given therapeutic modality should be proven by well …

Allergen-specific immunotherapy (AIT) can alter the natural course of an allergic disease. It
is widely held that the efficacy of a given therapeutic modality should be proven by well …