Cyclic di-AMP: another second messenger enters the fray

RM Corrigan, A Gründling - Nature Reviews Microbiology, 2013 - nature.com
Nucleotide signalling molecules contribute to the regulation of cellular pathways in all forms
of life. In recent years, the discovery of new signalling molecules in bacteria and archaea, as …

Molecular mechanisms for bacterial potassium homeostasis

J Stautz, Y Hellmich, MF Fuss, JM Silberberg… - Journal of molecular …, 2021 - Elsevier
Potassium ion homeostasis is essential for bacterial survival, playing roles in
osmoregulation, pH homeostasis, regulation of protein synthesis, enzyme activation …

Feedback control of two-component regulatory systems

EA Groisman - Annual review of microbiology, 2016 - annualreviews.org
Two-component systems are a dominant form of bacterial signal transduction. The
prototypical two-component system consists of a sensor that responds to a specific input (s) …

[HTML][HTML] The potential health benefits of gallic acid: Therapeutic and food applications

M Hadidi, R Liñán-Atero, M Tarahi, MC Christodoulou… - Antioxidants, 2024 - mdpi.com
Gallic acid (GA), a phenolic acid found in fruits and vegetables, has been consumed by
humans for centuries. Its extensive health benefits, such as antimicrobial, antioxidant …

[HTML][HTML] Two-component systems of S. aureus: signaling and sensing mechanisms

L Bleul, P Francois, C Wolz - Genes, 2022 - mdpi.com
Genes | Free Full-Text | Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms
Next Article in Journal Genome-Wide Identification, Primary Functional Characterization of the …

Bacterial Mg2+ Homeostasis, Transport, and Virulence

EA Groisman, K Hollands, MA Kriner… - Annual review of …, 2013 - annualreviews.org
Organisms must maintain physiological levels of Mg2+ because this divalent cation is critical
for the stabilization of membranes and ribosomes, for the neutralization of nucleic acids, and …

Adaptation to adversity: the intermingling of stress tolerance and pathogenesis in enterococci

AO Gaca, JA Lemos - Microbiology and Molecular Biology …, 2019 - Am Soc Microbiol
Enterococcus is a diverse and rugged genus colonizing the gastrointestinal tract of humans
and numerous hosts across the animal kingdom. Enterococci are also a leading cause of …

[HTML][HTML] Roles of two-component regulatory systems in Klebsiella pneumoniae: Regulation of virulence, antibiotic resistance, and stress responses

L Li, J Ma, P Cheng, M Li, Z Yu, X Song, Z Yu… - Microbiological …, 2023 - Elsevier
Klebsiella pneumoniae is an opportunistic pathogen belonging to the Enterobacteriaceae
family, which is the leading cause of nosocomial infections. The emergence of hypervirulent …

c-di-AMP: an essential molecule in the signaling pathways that regulate the viability and virulence of Gram-positive bacteria

T Fahmi, GC Port, KH Cho - Genes, 2017 - mdpi.com
Signal transduction pathways enable organisms to monitor their external environment and
adjust gene regulation to appropriately modify their cellular processes. Second messenger …

Binding of cyclic di-AMP to the Staphylococcus aureus sensor kinase KdpD occurs via the universal stress protein domain and downregulates the expression of the …

JA Moscoso, H Schramke, Y Zhang, T Tosi… - Journal of …, 2016 - Am Soc Microbiol
Nucleotide signaling molecules are important intracellular messengers that regulate a wide
range of biological functions. The human pathogen Staphylococcus aureus produces the …