The ability to construct a peptide or protein in a spatio-specific manner is of great interest for
therapeutic and biochemical research. However, the various functional groups present in …

Since its discovery in 1991, the bacterial periplasmic oxidative folding catalyst DsbA has
been the focus of intense research. Early studies addressed why it is so oxidizing and how it …

Highlights•Selenocysteine endows proteins with novel redox properties.•New recombinant
and chemical methods are facilitating selenoprotein production.•Many natural …

In this report, cell-penetrating streptavidin (CPS) is introduced to exploit the full power of
streptavidin–biotin biotechnology in cellular uptake. For this purpose, transporters, here …

Background Disulfide-rich proteins or DRPs are versatile bioactive compounds that
encompass a wide variety of pharmacological, therapeutic, and/or biotechnological …

The damage caused by oxidative and glycative stress to cells accumulates on a daily basis
and accelerates aging. Glutathione (GSH), a major antioxidant molecule in living organisms …

Dynamic combinatorial chemistry with diselenides and disulfides in water - Chemical
Communications (RSC Publishing) DOI:10.1039/C4CC00523F Royal Society of Chemistry …

Here we report a unique reaction between phenyl diselenide-ester substrates and H2S to
form 1, 2-benzothiaselenol-3-one. This reaction proceeded rapidly under mild conditions …

Cyclic oligochalcogenides are emerging as powerful tools to penetrate cells. With disulfide
ring tension maximized, selenium chemistry had to be explored next to enhance speed and …

The protein disulfide isomerase (PDI) family, found in the endoplasmic reticulum (ER) of the
eukaryotic cell, catalyzes the formation and cleavage of disulfide bonds and thereby helps in …