Therapeutic implications of caffeic acid in cancer and neurological diseases

M Alam, S Ahmed, AM Elasbali, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA
and its derivatives have been used for many centuries due to their natural healing and …

Neuroprotective effects of coffee bioactive compounds: a review

K Socała, A Szopa, A Serefko, E Poleszak… - International journal of …, 2020 - mdpi.com
Coffee is one of the most widely consumed beverages worldwide. It is usually identified as a
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …

The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase …

İ Gülçin, A Scozzafava, CT Supuran… - Journal of enzyme …, 2016 - Taylor & Francis
Caffeic acid phenethyl ester (CAPE) is an active component of honeybee propolis extracts.
Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread and intensively studied …

Neurological effects of honey: current and future prospects

M Mijanur Rahman, SH Gan… - … and Alternative Medicine, 2014 - Wiley Online Library
Honey is the only insect‐derived natural product with therapeutic, traditional, spiritual,
nutritional, cosmetic, and industrial value. In addition to having excellent nutritional value …

Caffeic acid attenuates neuroinflammation and cognitive impairment in streptozotocin-induced diabetic rats: Pivotal role of the cholinergic and purinergic signaling …

MFV Castro, CE Assmann, N Stefanello… - The Journal of …, 2023 - Elsevier
The present study evaluated the effect of caffeic acid (CA) on behavioral learning and
memory tasks in the diabetic state. We also evaluated the effect of this phenolic acid on the …

Honeybee products: An updated review of neurological actions

HR El-Seedi, SAM Khalifa, A Abd El-Wahed… - Trends in Food Science …, 2020 - Elsevier
Abstract Background According to the World Health Organization, two billion people will
attain the age of 60 years or more by 2050. Ageing is a major risk factor for a number of …

[HTML][HTML] Caffeic acid and ellagic acid ameliorate adjuvant-induced arthritis in rats via targeting inflammatory signals, chitinase-3-like protein-1 and angiogenesis

EM Fikry, AM Gad, AH Eid, HH Arab - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory arthropathy that principally attacks the
joints. The present study aimed to explore the potential anti-arthritic effects of caffeic acid …

Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats

R Deshmukh, M Kaundal, V Bansal - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Oxidative stress has been implicated in cognitive decline as seen during normal aging and
in sporadic Alzheimer's disease (AD). Caffeic acid, a polyphenolic compound, has been …

Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative, cholinergic activities and reduced oxidative stress

NS Rahim, SM Lim, V Mani… - Pharmaceutical …, 2017 - Taylor & Francis
Context: Virgin coconut oil (VCO) has been reported to possess antioxidative, anti-
inflammatory and anti-stress properties. Objective: Capitalizing on these therapeutic effects …

Anticholinesterase activity of selected phenolic acids and flavonoids-interaction testing in model solutions

D Szwajgier - Annals of Agricultural and Environmental Medicine, 2015 - agro.icm.edu.pl
Introduction. Alzheimer's disease is a progressively developing neurodegenerative disorder
of the central nervous system. The only present treatment of this disease is the use of acetyl …