This review delves into recent advances and significant breakthroughs in the field of the
catalytic Friedel–Crafts alkylation of targeted arenes or heteroarenes. Though a few earlier …

Indole, widely recognized as a versatile category of heterocyclic frameworks that contain
nitrogen is extensively employed in the synthesis of various organic compounds due to their …

The development of general and more sustainable heterogeneous catalytic processes for
Friedel–Crafts (FC) alkylation reactions is a key objective of interest for the synthesis of …

The development of one-pot, atom, and step-economic new methods avoiding metal, harsh
reaction conditions, and toxic reagents for the synthesis of medicinally important hybrid …

The first total synthesis of cadinane sesquiterpenoid alanense A, in which an intramolecular
dehydrative Friedel–Crafts alkylation of 2, 5-diaryl-2-pentanol is incorporated as a key step …

The facile and efficient synthesis of a unique class of 4-aryl-hydrocoumarins having
enormous applications in medicinal chemistry and natural products is presented. We have …

Hydroarylation of alkenes is one of the most straightforward and atom-economical strategy
for the construction of multi-aryl-substituted alkanes, but systematic studies have been …

In this work, we developed a facile and controllable electrophilic aromatic nitration method
with commercially available 68% HNO3 as the nitrating reagent and …

In the past 5 years, hexafluoroisopropanol (HFIP) has been used as a unique solvent or
additive to enable challenging transformations through substrate activation and stabilization …

A facile and efficient approach for the synthesis of multisubstituted tetrahydropyridazines
starting from cyclopropyl ketones and hydrazines has been developed. The transformation is …