Recent advances in microfluidic technology for bioanalysis and diagnostics

SF Berlanda, M Breitfeld, CL Dietsche… - Analytical …, 2020 - ACS Publications
Microfluidics has become a mature technology, providing an excellent toolbox for the
handling and manipulation of fluid samples, suspended cells, and particles. About 30 years …

Single-cell microfluidic impedance cytometry: From raw signals to cell phenotypes using data analytics

C Honrado, P Bisegna, NS Swami, F Caselli - Lab on a Chip, 2021 - pubs.rsc.org
The biophysical analysis of single-cells by microfluidic impedance cytometry is emerging as
a label-free and high-throughput means to stratify the heterogeneity of cellular systems …

A neural network approach for real-time particle/cell characterization in microfluidic impedance cytometry

C Honrado, JS McGrath, R Reale, P Bisegna… - Analytical and …, 2020 - Springer
Microfluidic applications such as active particle sorting or selective enrichment require
particle classification techniques that are capable of working in real time. In this paper, we …

[HTML][HTML] Fluid flow to mimic organ function in 3D in vitro models

Y Juste-Lanas, S Hervas-Raluy, JM García-Aznar… - APL …, 2023 - pubs.aip.org
Many different strategies can be found in the literature to model organ physiology, tissue
functionality, and disease in vitro; however, most of these models lack the physiological fluid …

Real-time precise microfluidic droplets label-sequencing combined in a velocity detection sensor

R Zamboni, A Zaltron, M Chauvet, C Sada - Scientific Reports, 2021 - nature.com
Droplets microfluidics is broadening the range of Lab on a Chip solutions that, however, still
suffer from the lack of an adequate level of integration of optical detection and sensors. In …

Label‐free monitoring and manipulation of microfluidic water‐in‐oil droplets

C Frey, J Pfeil, T Neckernuss, D Geiger, K Weishaupt… - View, 2020 - Wiley Online Library
Droplet‐based microfluidic technology offers several benefits: the integration of multiple
laboratory functions into a single microfabricated chip, manual intervention possibilities …

A Bayesian approach for coincidence resolution in microfluidic impedance cytometry

F Caselli, A De Ninno, R Reale… - IEEE Transactions …, 2020 - ieeexplore.ieee.org
Objective: Cell counting and characterization is fundamental for medicine, science and
technology. Coulter-type microfluidic devices are effective and automated systems for …

[HTML][HTML] A microfluidic droplet system for ultra-monodisperse droplet generation: A universal approach

A Kalantarifard, E Alizadeh-Haghighi… - Chemical Engineering …, 2022 - Elsevier
Despite the importance of droplet monodispersity, a universal methodology for high
monodispersity droplet generation does not exist yet. We have recently demonstrated that …

A review on intelligent impedance cytometry systems: Development, applications and advances

T Tang, T Julian, D Ma, Y Yang, M Li, Y Hosokawa… - Analytica Chimica …, 2023 - Elsevier
Impedance cytometry is a well-established technique for counting and analyzing single
cells, with several advantages, such as convenience, high throughput, and no labeling …

CO2 laser machining for microfluidics mold fabrication from PMMA with applications on viscoelastic focusing, electrospun nanofiber production, and droplet …

MT Guler, M Inal, I Bilican - Journal of Industrial and Engineering Chemistry, 2021 - Elsevier
In this study, a new method for the fabrication of polydimethylsiloxane (PDMS)
microchannels through the replication of plexiglass molds was developed. A plexiglass slab …