Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …

Many of melatonin's actions are mediated through interaction with the G-protein coupled
membrane bound melatonin receptors type 1 and type 2 (MT1 and MT2, respectively) or …

Melatonin, the neurohormone of the pineal gland, is also produced by various other tissues
and cells. It acts via G protein-coupled receptors expressed in various areas of the central …

In humans, an adaptable internal biological system generates circadian rhythms that
maintain synchronicity of behavior and physiology with the changing demands of the 24-h …

Currently, in developed countries, nights are excessively illuminated (light at night), whereas
daytime is mainly spent indoors, and thus people are exposed to much lower light intensities …

Melatonin, dubbed the hormone of darkness, is known to regulate a wide variety of
physiological processes in mammals. This review describes well-defined functional …

Evidence is accumulating regarding the importance of circadian core oscillators, several
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …

The purpose of this systematic review is to access the current state of knowledge concerning
the role for melatonin in human pregnancy. Melatonin is a neuroendocrine hormone …

Over recent years, a deeper comprehension of the molecular mechanisms that control
biological clocks and circadian rhythms has been achieved. In fact, many studies have …

Melatonin is an indoleamine produced by the pineal gland and secreted in a circadian
manner. In the past few decades, research over this topic has been enhanced. Melatonin …