Implant surface design has evolved to meet oral rehabilitation challenges in both healthy
and compromised bone. For example, to conquer the most common dental implant-related …

Osteomyelitis is a devastating disease caused by microbial infection of bone. While the
frequency of infection following elective orthopedic surgery is low, rates of reinfection are …

As the number of total joint arthroplasty and internal fixation procedures continues to rise,
the threat of infection following surgery has significant clinical implications. These infections …

Bone plates play a vital role in bone fracture healing by providing the necessary mechanical
fixation for fracture fragments through modulating biomechanical microenvironment adjacent …

Implant related infections are the most common cause of joint arthroplasty failure, requiring
revision surgeries and a new implant, resulting in a cost of $8.6 billion annually. To address …

Polyetheretherketone (PEEK) has been widely applied in biomedical engineering. However,
the unsatisfactory bioactivity essentially limits the clinical application of PEEK. In this study, a …

Prosthesis-related infection is a serious complication for patients after orthopedic joint
replacement, which is currently difficult to treat with antibiotic therapy. Consequently, in most …

Staphylococcus aureus (S. aureus) osteomyelitis is a significant complication for
orthopaedic patients undergoing surgery, particularly with fracture fixation and arthroplasty …

The clinical impact of bacterial infections on bone regeneration has been incompletely
quantified and documented. As a result, controversy exists about the optimal treatment …

Despite advances in orthopaedic materials, the development of drug-eluting bone and joint
implants that can sustain the delivery of the drug and maintain the necessary mechanical …