Precision oncology medicine: the clinical relevance of patient‐specific biomarkers used to optimize cancer treatment
KT Schmidt, CH Chau, DK Price… - The Journal of Clinical …, 2016 - Wiley Online Library
Precision medicine in oncology is the result of an increasing awareness of patient‐specific
clinical features coupled with the development of genomic‐based diagnostics and targeted …
clinical features coupled with the development of genomic‐based diagnostics and targeted …
[HTML][HTML] The era of multigene panels comes? The clinical utility of oncotype DX and MammaPrint
Abstract The AJCC Cancer Staging Manual, eighth edition published in late 2016, will
become the new global guideline for cancer diagnosis and treatment from January 1, 2018 …
become the new global guideline for cancer diagnosis and treatment from January 1, 2018 …
Validated biomarkers: The key to precision treatment in patients with breast cancer
MJ Duffy, N O'Donovan, E McDermott, J Crown - The Breast, 2016 - Elsevier
Recent DNA sequencing and gene expression studies have shown that at a molecular level,
almost every case of breast cancer is unique and different from other breast cancers. For …
almost every case of breast cancer is unique and different from other breast cancers. For …
Utilization and impact of 21-gene recurrence score assay for breast cancer in clinical practice across the United States: lessons learned from the 2010 to 2012 …
A Orucevic, RE Heidel, JL Bell - Breast cancer research and treatment, 2016 - Springer
The aim of our study is to investigate patient selection for the 21-gene recurrence score
assay (RS) for breast cancer (BC) and the RS impact on chemotherapy administration …
assay (RS) for breast cancer (BC) and the RS impact on chemotherapy administration …
EndoPredict® in early hormone receptor-positive, HER2-negative breast cancer
K Almstedt, S Mendoza, M Otto, MJ Battista… - Breast cancer research …, 2020 - Springer
Purpose Evaluating consecutive early breast cancer patients, we analyzed both the impact
of EndoPredict® on clinical decisions as well as clinico-pathological factors influencing the …
of EndoPredict® on clinical decisions as well as clinico-pathological factors influencing the …
Impact of TAILORx on chemotherapy prescribing and 21‐gene recurrence score–guided treatment costs in a population‐based cohort of patients with breast cancer
Background The trial assigning individualized options for treatment (Rx)(TAILORx)
confirmed the predictive value of the 21‐gene recurrence score (RS) assay in hormone …
confirmed the predictive value of the 21‐gene recurrence score (RS) assay in hormone …
Question prompt list to support patient-provider communication in the use of the 21-gene recurrence test: feasibility, acceptability, and outcomes
J Jayasekera, ST Vadaparampil, S Eggly… - JCO oncology …, 2020 - ascopubs.org
PURPOSE: The 21-gene recurrence score (RS) assay is used to guide breast cancer
treatment decisions but can be poorly understood by patients. We examined the effects of a …
treatment decisions but can be poorly understood by patients. We examined the effects of a …
Measures of appropriateness and value for breast surgeons and their patients: the American society of breast surgeons choosing wisely® Initiative
J Landercasper, L Bailey, TS Berry, RR Buras… - Annals of surgical …, 2016 - Springer
Background Current breast cancer care is based on high-level evidence from randomized,
controlled trials. Despite these data, there continues to be variability of breast cancer care …
controlled trials. Despite these data, there continues to be variability of breast cancer care …
Adherence disparities and utilization trends of oncotype DX assay: a national cancer database study
S Chen, C Thacker, S Wang, KA Young… - Journal of Surgical …, 2023 - Elsevier
Abstract Introduction Oncotype Dx (ODX) is a genetic assay that analyzes tumor recurrence
risk and provides chemotherapy recommendations for T1-T2 stage, hormone receptor …
risk and provides chemotherapy recommendations for T1-T2 stage, hormone receptor …
Discordance in 21-gene recurrence scores between paired breast cancer samples is inversely associated with patient age
Abstract Background The Oncotype DX 21-gene Recurrence Score is a genomic-based
algorithm that guides adjuvant chemotherapy treatment decisions for women with early …
algorithm that guides adjuvant chemotherapy treatment decisions for women with early …