The placenta is the chief regulator of nutrient supply to the growing embryo during gestation.
As such, adequate placental function is instrumental for developmental progression …

Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …

Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

The placenta is arguably the most important organ of the body, but paradoxically the most
poorly understood. During its transient existence, it performs actions that are later taken on …

Normal mammalian development requires a maternal and paternal contribution, which is
attributed to imprinted genes, or genes that are expressed from a single parental allele …

Appropriate fetal growth relies upon adequate placental nutrient transfer. Birthweight:
placental weight ratio (BW: PW ratio) is often used as a proxy for placental efficiency, defined …

The environment in which the fetus develops is critical for its survival and long-term health.
The regulation of normal human fetal growth involves many multidirectional interactions …

BACKGROUND The placenta is of utmost importance for intrauterine fetal development and
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …

Hematopoietic stem cells (HSCs) develop during embryogenesis in a complex process that
involves multiple anatomical sites. Once HSC precursors have been specified from …

The placenta is essential for sustaining the growth of the fetus during gestation, and defects
in its function result in fetal growth restriction or, if more severe, fetal death. Several …