Research progress on the pathogenesis of knee osteoarthritis

X Du, Z Liu, X Tao, Y Mei, D Zhou, K Cheng… - Orthopaedic …, 2023 - Wiley Online Library
Knee osteoarthritis (KOA) is a chronic joint bone disease characterized by inflammatory
destruction and hyperplasia of bone. Its main clinical symptoms are joint mobility difficulties …

Undenatured type II collagen and its role in improving osteoarthritis

R Xu, J Wu, L Zheng, M Zhao - Ageing Research Reviews, 2023 - Elsevier
Osteoarthritis (OA) is a degenerative joint disease, affecting 32.5 million US adults or 242
million people worldwide. There is no cure for OA. Many animal and clinical trials showed …

[HTML][HTML] Unraveling NEAT1's complex role in lung cancer biology: a comprehensive review

MS Hussain, O Afzal, G Gupta, A Goyal, WH Almalki… - EXCLI …, 2024 - ncbi.nlm.nih.gov
This review delves into the pivotal role of the long non-coding RNA NEAT1 in cancer
biology, particularly in lung cancer (LC). It emphasizes NEAT1's unique subcellular …

Effects of genus Epimedium in the treatment of osteoarthritis and relevant signaling pathways

X Tong, Y Wang, B Dong, Y Li, S Lang, J Ma, X Ma - Chinese Medicine, 2023 - Springer
Osteoarthritis (OA) is a common chronic degenerative joint disease in clinical practice with a
high prevalence, especially in the elderly. Traditional Chinese Medicine (TCM) believes that …

Mulberry Leaf Polysaccharides Attenuate Oxidative Stress Injury in Peripheral Blood Leukocytes by Regulating Endoplasmic Reticulum Stress

W Jiang, Y Lin, L Qian, S Lu, H Shen, X Ge, L Miao - Antioxidants, 2024 - mdpi.com
The present study assessed the protective effects and underlying mechanisms of mulberry
leaf polysaccharides (MLPs) against hydrogen peroxide (H2O2)-induced oxidative stress …

Natural anti‐inflammatory products for osteoarthritis: From molecular mechanism to drug delivery systems and clinical trials

J Su, M Yu, H Wang, Y Wei - Phytotherapy Research, 2023 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease that affects millions globally. The present
nonsteroidal anti‐inflammatory drug treatments have different side effects, leading …

The emerging role of lncRNAs in osteoarthritis development and potential therapy

X Zhang, Q Liu, J Zhang, C Song, Z Han, J Wang… - Frontiers in …, 2023 - frontiersin.org
Osteoarthritis impairs the functions of various joints, such as knees, hips, hands and spine,
which causes pain, swelling, stiffness and reduced mobility in joints. Multiple factors …

Polysaccharide nanosystems for osteoarthritis therapy: Mechanisms, combinations, and future directions

S Shi, L Zhang, K Jiang - International Journal of Biological …, 2024 - Elsevier
Osteoarthritis (OA) represents a chronic degenerative joint ailment characterized by the
gradual breakdown of cartilage, inflicting substantial physical and economic burdens …

LncRNA MALAT1 promotes osteogenic differentiation through the miR‐93‐5p/SMAD5 axis

Y Gu, Y Bai - Oral Diseases, 2024 - Wiley Online Library
Objectives Promoting the osteogenic differentiation of periodontal ligament stem cells
(PDLSCs) is a way to regenerate periodontal bone. This study aimed to determine whether …

Phytochemicals against osteoarthritis by inhibiting apoptosis

H Kong, JJ Han, G Dmitrii, X Zhang - Molecules, 2024 - mdpi.com
Osteoarthritis (OA) is a chronic joint disease that causes pathological changes in articular
cartilage, synovial membrane, or subchondral bone. Conventional treatments for OA include …