Introduction: In recent years, the number of active pharmaceutical ingredients with high
therapeutic impact, but very low water solubility, has increased significantly. Thus, a great …

Introduction: Over the past few decades, the domain of drug formulations has
metamorphosed from the conventional tablets and capsules to advanced and intricate drug …

Introduction: Present article reviews solid dispersion (SD) technologies and other patented
inventions in the area of pharmaceutical SDs, which provide stable amorphous SDs. Areas …

Poor solubility is an ongoing issue and the graph of poorly soluble drugs has increased
markedly which critically affect their dissolution, bioavailability, and clinical effects. This …

Poorly water-soluble drug substances that exhibit high melting points are difficult to process
by melt extrusion due to chemical instability at high temperatures required for processing …

The purpose of this research was to evaluate the effect of the HPC (hydroxypropylcellulose)
and Tween 80 on the physicochemical properties and oral bioavailability of ezetimibe …

The objective of this study was to improve the dissolution and solubility of dexibuprofen
(DEX) using hydroxypropyl beta cyclodextrin (HPβCD) inclusion complexes and also to …

Due to the high number of poorly soluble drugs in the development pipeline, novel
processes for delivery of these challenging molecules are increasingly in demand. One such …

The objective of this study was to enhance dissolution and permeation of a low soluble,
absorbable fexofenadine hydrochloride (FFH) by preparing solid dispersions using …

Solid dispersion (SD) is one of the oldest and widely utilized techniques to improve the
solubility of slowly dissolving drugs. A variety of pharmaceutically compatible additives using …