The generation of new lymphatic vessels through lymphangiogenesis and the remodelling
of existing lymphatics are thought to be important steps in cancer metastasis. The past …

Endometriosis is a benign gynecological disorder characterized by the presence of tissue
resembling the endometrium in locations outside the uterus. The pathogenesis of …

Cutaneous malignant melanomas originate primarily within epidermal melanocytic cells.
Melanoma cells share many characteristics with melanocyte precursors, suggesting that …

Vascular endothelial growth factor C (VEGF-C) has been identified as a multifaceted factor
participating in the regulation of tumor angiogenesis and lymphangiogenesis. VEGF-C is not …

The lymphatic vasculature has been widely described and explored for its key functions in
fluid homeostasis and in the organization and modulation of the immune response. Besides …

Vascular endothelial growth factor‐C (VEGF‐C) binds to receptor vascular endothelial
growth factor receptor‐3 (VEGFR‐3) expressed on lymphatic endothelial and melanoma …

Background As lymphatic vessel is a major route for solid tumor metastasis, they are
considered an essential part of tumor drainage conduits. Apart from forming the walls of …

The possibility to modulate ex vivo human NK cell differentiation towards specific
phenotypes will contribute to a better understanding of NK cell differentiation and facilitate …

Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's
sarcoma (KS), which is one of the most common HIV-associated neoplasms. The …

Cutaneous malignant melanoma is an aggressive tumor characterized by early lymph node
metastasis and bad prognosis. Although the spread of tumor cells in the regional lymph …