Renal aging: causes and consequences

ED O'Sullivan, J Hughes… - Journal of the American …, 2017 - journals.lww.com
Individuals age> 65 years old are the fastest expanding population demographic throughout
the developed world. Consequently, more aged patients than before are receiving …

Advanced glycation end products: key players in skin aging?

P Gkogkolou, M Böhm - Dermato-endocrinology, 2012 - Taylor & Francis
Aging is the progressive accumulation of damage to an organism over time leading to
disease and death. Aging research has been very intensive in the last years aiming at …

Cellular senescence, vascular disease, and aging: part 2 of a 2-part review: clinical vascular disease in the elderly

JC Kovacic, P Moreno, EG Nabel, V Hachinski… - Circulation, 2011 - Am Heart Assoc
The increasing prevalence of older-age people in our society represents the culmination of
centuries of medical, scientific, and social endeavors. At least in Western society, now …

[HTML][HTML] Role of advanced glycation end products in mobility and considerations in possible dietary and nutritional intervention strategies

JH Chen, X Lin, C Bu, X Zhang - Nutrition & metabolism, 2018 - Springer
Advanced glycation end products (AGEs), a group of compounds that are formed by non-
enzymatic reactions between carbonyl groups of reducing sugars and free amino groups of …

AGE restriction in diabetes mellitus: a paradigm shift

H Vlassara, GE Striker - Nature Reviews Endocrinology, 2011 - nature.com
Persistently elevated oxidative stress and inflammation precede or occur during the
development of type 1 or type 2 diabetes mellitus and precipitate devastating complications …

[HTML][HTML] Dietary AGEs as exogenous boosters of inflammation

ME Garay-Sevilla, A Rojas, M Portero-Otin, J Uribarri - Nutrients, 2021 - mdpi.com
Most chronic modern non-transmissible diseases seem to begin as the result of low-grade
inflammation extending over prolonged periods of time. The importance of diet as a source …

Role of AGEs-RAGE system in cardiovascular disease

K Fukami, S Yamagishi, S Okuda - Current pharmaceutical …, 2014 - ingentaconnect.com
Advanced glycation end products (AGEs) are a heterogenous group of molecules formed
during a non-enzymatic reaction between proteins and sugar residues. Recently, AGEs and …

Dietary advanced glycation end products (dAGEs): An insight between modern diet and health

Z Tian, S Chen, Y Shi, P Wang, Y Wu, G Li - Food Chemistry, 2023 - Elsevier
Advanced glycation end products (AGEs) are formed by a series of chemical reactions of
amino acids, peptides, proteins, and ketones at normal temperature or heated non …

Glycation‐altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age‐related disease (in nondiabetics)

T Uchiki, KA Weikel, W Jiao, F Shang, A Caceres… - Aging cell, 2012 - Wiley Online Library
Epidemiologic studies indicate that the risks for major age‐related debilities including
coronary heart disease, diabetes, and age‐related macular degeneration (AMD) are …

Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging process–a mini-review

TH Fleming, PM Humpert, PP Nawroth, A Bierhaus - Gerontology, 2011 - karger.com
Aging is a dynamic process in which its rate and subsequent longevity of an organism are
dependent upon the balance between the reactive intermediates of normal cellular …