Anti-inflammatory and anticancer effects of microalgal carotenoids

J Ávila-Román, S García-Gil, A Rodríguez-Luna… - Marine Drugs, 2021 - mdpi.com
Acute inflammation is a key component of the immune system's response to pathogens, toxic
agents, or tissue injury, involving the stimulation of defense mechanisms aimed to removing …

Association between β-carotene supplementation and risk of cancer: a meta-analysis of randomized controlled trials

Y Zhang, J Yang, X Na, A Zhao - Nutrition Reviews, 2023 - academic.oup.com
Context β-Carotene, which is derived from most fruits and vegetables, is the most common
type of carotenes. Existing studies have demonstrated that β-carotene is associated with …

Zeaxanthin induces apoptosis via ROS-regulated MAPK and AKT signaling pathway in human gastric cancer cells

YN Sheng, YH Luo, SB Liu, WT Xu, Y Zhang… - OncoTargets and …, 2020 - Taylor & Francis
Background Zeaxanthin, a carotenoid commonly found in plants, has a variety of biological
functions including anti-cancer activity. Purpose This study aimed to investigate the potential …

Green leafy vegetable and lutein intake and multiple health outcomes

N Li, X Wu, W Zhuang, L Xia, Y Chen, Y Wang, C Wu… - Food chemistry, 2021 - Elsevier
Green leafy vegetables (GLVs) are a key element of healthy eating patterns and are an
important source of lutein. To clarify the evidence for associations between GLVs and lutein …

Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS mice

M Terasaki, O Uehara, S Ogasa, T Sano… - …, 2021 - academic.oup.com
Fucoxanthin (Fx), a marine carotenoid found in edible brown algae, is well known for having
anticancer properties. The gut microbiota has been demonstrated as a hallmark for …

Carotenoids in cancer metastasis—Status quo and outlook

L Koklesova, A Liskova, M Samec, K Zhai, M Abotaleb… - Biomolecules, 2020 - mdpi.com
Metastasis represents a major obstacle in cancer treatment and the leading cause of cancer-
related deaths. Therefore, the identification of compounds targeting the multi-step and …

Inverse association of serum carotenoid levels with prevalence of hypertension in the general adult population

X Zhu, M Shi, H Pang, I Cheang, Q Zhu, Q Guo… - Frontiers in …, 2022 - frontiersin.org
Carotenoid levels are inversely associated with blood pressure (BP). This study focused on
the effects of individual and combined serum carotenoids on BP and hypertension, which …

Epigenetic drugs as new emerging therapeutics: What is the scale's orientation of application and challenges?

MR Farani, M Sarlak, A Gholami, M Azaraian… - … -Research and Practice, 2023 - Elsevier
Epigenetics is the study of heritable changes in gene expression or function without altering
the DNA sequence. Important factors are part of epigenetic events, such as methylation …

Vitamin A and retinoids in bladder cancer chemoprevention and treatment: a narrative review of current evidence, challenges and future prospects

L Tratnjek, J Jeruc, R Romih, D Zupančič - International journal of …, 2021 - mdpi.com
Bladder cancer (BC) is the tenth most common cancer worldwide with a high recurrence
rate, morbidity and mortality. Therefore, chemoprevention and improved treatment of BC are …

Carrot and carotene and multiple health outcomes: an umbrella review of the evidence

X Yi, J Li, D Liao, G Peng, X Zheng… - Journal of the …, 2023 - Wiley Online Library
In recent years, the benefits of carrots and carotene in different areas of health have been
examined. The purpose of this umbrella review was to identify the associations between …