[HTML][HTML] Insights from deep sequencing of the HBV genome—unique, tiny, and misunderstood
Hepatitis B virus (HBV) is a unique, tiny, partially double-stranded, reverse-transcribing DNA
virus with proteins encoded by multiple overlapping reading frames. The substitution rate is …
virus with proteins encoded by multiple overlapping reading frames. The substitution rate is …
Epidemiological data analysis of viral quasispecies in the next-generation sequencing era
The unprecedented coverage offered by next-generation sequencing (NGS) technology has
facilitated the assessment of the population complexity of intra-host RNA viral populations at …
facilitated the assessment of the population complexity of intra-host RNA viral populations at …
QUENTIN: reconstruction of disease transmissions from viral quasispecies genomic data
Motivation Genomic analysis has become one of the major tools for disease outbreak
investigations. However, existing computational frameworks for inference of transmission …
investigations. However, existing computational frameworks for inference of transmission …
A large HCV transmission network enabled a fast-growing HIV outbreak in rural Indiana, 2015
S Ramachandran, H Thai, JC Forbi, RR Galang… - …, 2018 - thelancet.com
Abstract Background A high prevalence (92.3%) of hepatitis C virus (HCV) co-infection
among HIV patients identified during a large HIV outbreak associated with injection of …
among HIV patients identified during a large HIV outbreak associated with injection of …
Transmission of hepatitis C virus in the dialysis setting and strategies for its prevention
DB Nguyen, D Bixler, PR Patel - Seminars in dialysis, 2019 - Wiley Online Library
Hepatitis C virus (HCV) infection is more common among hemodialysis patients than the
general population and transmission of HCV in dialysis clinics has been reported. In the …
general population and transmission of HCV in dialysis clinics has been reported. In the …
Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reduction
Rapidly evolving RNA viruses continuously produce minority haplotypes that can become
dominant if they are drug-resistant or can better evade the immune system. Therefore, early …
dominant if they are drug-resistant or can better evade the immune system. Therefore, early …
GHOST: global hepatitis outbreak and surveillance technology
Background Hepatitis C is a major public health problem in the United States and
worldwide. Outbreaks of hepatitis C virus (HCV) infections associated with unsafe injection …
worldwide. Outbreaks of hepatitis C virus (HCV) infections associated with unsafe injection …
[HTML][HTML] Global transmission network of SARS-CoV-2: from outbreak to pandemic
Background. The COVID-19 pandemic caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is straining health systems around the world. Although the …
coronavirus 2 (SARS-CoV-2) is straining health systems around the world. Although the …
The distribution of hepatitis C viral genotypes shifted among chronic hepatitis C patients in Yunnan, China, between 2008–2018
Object The hepatitis C virus (HCV) is prevalent across China, with a distinctive genotypic
distribution that varies by geographical region and mode of transmission. Yunnan is one …
distribution that varies by geographical region and mode of transmission. Yunnan is one …
A model-based clustering method to detect infectious disease transmission outbreaks from sequence variation
RM McCloskey, AFY Poon - PLoS computational biology, 2017 - journals.plos.org
Clustering infections by genetic similarity is a popular technique for identifying potential
outbreaks of infectious disease, in part because sequences are now routinely collected for …
outbreaks of infectious disease, in part because sequences are now routinely collected for …