Ceruloplasmin and other copper binding components of blood plasma and their functions: an update

MC Linder - Metallomics, 2016 - academic.oup.com
We know that blood plasma contains many proteins and also other components that bind
copper. The largest contributor to copper in the plasma is ceruloplasmin, which accounts for …

Multi-copper oxidases and human iron metabolism

G Vashchenko, RTA MacGillivray - Nutrients, 2013 - mdpi.com
Multi-copper oxidases (MCOs) are a small group of enzymes that oxidize their substrate with
the concomitant reduction of dioxygen to two water molecules. Generally, multi-copper …

Ferroptosis mediates cuprizone-induced loss of oligodendrocytes and demyelination

P Jhelum, E Santos-Nogueira, W Teo… - Journal of …, 2020 - Soc Neuroscience
Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS. Cuprizone (CZ), a
copper chelator, is widely used to study demyelination and remyelination in the CNS, in the …

Automated matching of high-and low-resolution structural models

MB Kozin, DI Svergun - Journal of applied crystallography, 2001 - journals.iucr.org
A method is presented for automated best-matching alignment of three-dimensional models
represented by ensembles of points. A normalized spatial discrepancy (NSD) is introduced …

Crystal Structure of a Four-Copper Laccase Complexed with an Arylamine:  Insights into Substrate Recognition and Correlation with Kinetics,

T Bertrand, C Jolivalt, P Briozzo, E Caminade… - Biochemistry, 2002 - ACS Publications
Laccases are multicopper oxidases that catalyze the oxidation of a wide range of phenols or
arylamines, and their use in industrial oxidative processes is increasing. We purified from …

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

SL Stafford, NJ Bokil, MES Achard… - Bioscience …, 2013 - portlandpress.com
The immunomodulatory and antimicrobial properties of zinc and copper have long been
appreciated. In addition, these metal ions are also essential for microbial growth and …

Nature of the Intermediate Formed in the Reduction of O2 to H2O at the Trinuclear Copper Cluster Active Site in Native Laccase

SK Lee, SDB George, WE Antholine… - Journal of the …, 2002 - ACS Publications
The multicopper oxidases contain at least four copper atoms and catalyze the four-electron
reduction of O2 to H2O at a trinuclear copper cluster. An intermediate, termed native …

[图书][B] Handbook on metalloproteins

I Bertini, A Sigel - 2001 - taylorfrancis.com
This Handbook on Metalloproteins focuses on the available structural information of proteins
and their metal ion coordination spheres. It centers on the metal ions indispensable for life …

Structure to function relationships in ceruloplasmin: a'moonlighting'protein

P Bielli, L Calabrese - Cellular and Molecular Life Sciences CMLS, 2002 - Springer
Specialised copper sites have been recruited during evolution to provide long-range
electron transfer reactivity and oxygen binding and activation in proteins destined to cope …

Monoamine oxidases: certainties and uncertainties

KF Tipton, S Boyce, J O'Sullivan… - Current medicinal …, 2004 - ingentaconnect.com
A great deal has been learned about the behaviour of monoamine oxidase in the 75 years
since it was first discovered, but there is still a great deal left to understand. This review …