Conopeptides are a diverse group of recently evolved venom peptides used for prey capture
and/or defense. Each species of cone snails produces in excess of 1000 conopeptides, with …

Abstract Terlau, Heinrich, and Baldomero M. Olivera. Conus Venoms: A Rich Source of
Novel Ion Channel-Targeted Peptides. Physiol Rev 84: 41–68, 2004; 10.1152/physrev …

Covering: 2003. Previous review: Nat. Prod. Rep., 2004, 21, 1 This review covers the
literature published in 2003 for marine natural products, with 619 citations (413 for the …

Cone snails are carnivorous marine gastropods that have evolved potent venoms to capture
their prey. These venoms comprise a rich and diverse cocktail of peptide toxins, or …

Conotoxins are the peptidic components of the venoms of marine cone snails (genus
Conus). They are remarkably diverse in terms of structure and function. Unique potency and …

The venoms of predatory cone snails (genus Conus) have yielded a complex library of about
50–100,000 bioactive peptides, each believed to have a specific physiological target …

Animal venoms represent a vast library of bioactive peptides and proteins with proven
potential, not only as research tools but also as drug leads and therapeutics. This is …

Marine cone snails from the genus Conus are estimated to consist of up to 700 species.
These predatory molluscs have devised an efficient venom apparatus that allows them to …

In the four decades since toxinologists in Australia and elsewhere started to investigate the
active constituents of venomous cone snails, a wealth of information has emerged on the …

The large Ca2+-activated K+ channel (BK channel) reflects per excellence the dilemma of
the molecular target driven drug discovery process. Significant experimental evidence …