Cytoplasmic incompatibility (CI) is the most common symbiont-induced reproductive
manipulation. Specifically, symbiont-induced sperm modifications cause catastrophic mitotic …

Precise spatiotemporal regulation of gene expression is of paramount importance for
eukaryotic development. The maternal-to-zygotic transition (MZT) during early …

Oogenesis is a complex developmental process that involves spatiotemporally regulated
coordination between the germline and supporting, somatic cell populations. This process …

Meiotic drive loci distort the normally equal segregation of alleles, which benefits their own
transmission even in the face of severe fitness costs to their host organism. However …

Intracellular Wolbachia bacteria manipulate arthropod reproduction to promote their own
inheritance. The most prevalent mechanism, cytoplasmic incompatibility (CI), traces to a …

MRE11 nuclease forms a trimeric complex (MRN) with RAD50 and NBS1 and plays a
central role in preventing genomic instability. When DNA double-strand breaks (DSBs) …

Many species of arthropods carry maternally inherited bacterial endosymbionts that can
influence host sexual reproduction to benefit the bacterium. The most well-known of such …

Highlights•Meiotic drive genes are frequently composed of gene families.•Transposable
elements can drive meiotic gene family expansion.•Meiotic drive genes rapidly diversify and …

The union of haploid gametes at fertilization initiates the formation of the diploid zygote in
sexually reproducing animals. This founding event of embryogenesis includes several …

Identifying crucial proteins in protein-protein interaction (PPI) networks is essential for
understanding biological systems. However, the ambiguity of interaction strength hinders …