Astrocyte control of synaptic transmission and neurovascular coupling
PG Haydon, G Carmignoto - Physiological reviews, 2006 - journals.physiology.org
From a structural perspective, the predominant glial cell of the central nervous system, the
astrocyte, is positioned to regulate synaptic transmission and neurovascular coupling: the …
astrocyte, is positioned to regulate synaptic transmission and neurovascular coupling: the …
Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role and involvement in neurological disorders
JW Phillis, LA Horrocks, AA Farooqui - Brain research reviews, 2006 - Elsevier
Three enzyme systems, cyclooxygenases that generate prostaglandins, lipoxygenases that
form hydroxy derivatives and leukotrienes, and epoxygenases that give rise to …
form hydroxy derivatives and leukotrienes, and epoxygenases that give rise to …
Role of monocytes in atherogenesis
B Østerud, E Bjørklid - Physiological reviews, 2003 - journals.physiology.org
Østerud, Bjarne, and Eirik Bjørklid. Role of Monocytes in Atherogenesis. Physiol Rev 83:
1069-1112, 2003; 10.1152/physrev. 00005.2003.—This review focuses on the role of …
1069-1112, 2003; 10.1152/physrev. 00005.2003.—This review focuses on the role of …
Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K+ Channels and p42/p44 MAPK Pathway
J Seubert, B Yang, JA Bradbury, J Graves… - Circulation …, 2004 - Am Heart Assoc
Human CYP2J2 is abundant in heart and active in the biosynthesis of epoxyeicosatrienoic
acids (EETs); however, the functional role of this P450 and its eicosanoid products in the …
acids (EETs); however, the functional role of this P450 and its eicosanoid products in the …
Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system
Abstract Cytochrome P450s (P450) metabolize arachidonic acid (AA) to
hydroxyeicosatetraenoic acids (HETEs) and epoxyeicosatrienoic acids (EETs). Among these …
hydroxyeicosatetraenoic acids (HETEs) and epoxyeicosatrienoic acids (EETs). Among these …
Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer
W Yu, H Chai, Y Li, H Zhao, X Xie, H Zheng… - Toxicology and applied …, 2012 - Elsevier
Cytochrome P450 (CYP) 4Z1, a novel CYP4 family member, is over-expressed in human
mammary carcinoma and associated with high-grade tumors and poor prognosis. However …
mammary carcinoma and associated with high-grade tumors and poor prognosis. However …
Cytochrome P450 pathways of arachidonic acid metabolism
Cytochrome P450s metabolize arachidonic acid to hydroxyeicosatetraenoic acids and
epoxyeicosatrienoic acids. These eicosanoids are formed in a tissue and cell-specific …
epoxyeicosatrienoic acids. These eicosanoids are formed in a tissue and cell-specific …
Cytochrome P450-derived eicosanoids and heart function
KL Jamieson, T Endo, AM Darwesh… - Pharmacology & …, 2017 - Elsevier
The cytochrome P450 monooxygenase system (CYP) is a multigene superfamily of
enzymes, which are important in the metabolism of foreign and endogenous compounds …
enzymes, which are important in the metabolism of foreign and endogenous compounds …
Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function
JM Seubert, CJ Sinal, J Graves, LM DeGraff… - Circulation …, 2006 - Am Heart Assoc
Cytochrome P450 epoxygenases metabolize arachidonic acid to epoxyeicosatrienoic acids
(EETs) which are converted to dihydroxyeicosatrienoic acids (DHETs) by soluble epoxide …
(EETs) which are converted to dihydroxyeicosatrienoic acids (DHETs) by soluble epoxide …
20-HETE in the regulation of vascular and cardiac function
P Rocic, ML Schwartzman - Pharmacology & therapeutics, 2018 - Elsevier
HETE, the ω-hydroxylation product of arachidonic acid catalyzed by enzymes of the
cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent …
cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent …