Advances in Hydrogels in Organoids and Organs‐on‐a‐Chip
Significant advances in materials, microscale technology, and stem cell biology have
enabled the construction of 3D tissues and organs, which will ultimately lead to more …
enabled the construction of 3D tissues and organs, which will ultimately lead to more …
25th anniversary article: Rational design and applications of hydrogels in regenerative medicine
Hydrogels are hydrophilic polymer‐based materials with high water content and physical
characteristics that resemble the native extracellular matrix. Because of their remarkable …
characteristics that resemble the native extracellular matrix. Because of their remarkable …
Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing
Biomedical research has relied on animal studies and conventional cell cultures for
decades. Recently, microphysiological systems (MPS), also known as organs-on-chips, that …
decades. Recently, microphysiological systems (MPS), also known as organs-on-chips, that …
3D printed drug delivery and testing systems—a passing fad or the future?
Abstract The US Food and Drug Administration approval of the first 3D printed tablet in 2015
has ignited growing interest in 3D printing, or additive manufacturing (AM), for drug delivery …
has ignited growing interest in 3D printing, or additive manufacturing (AM), for drug delivery …
Organ‐on‐a‐Chip Systems: microengineering to biomimic living systems
“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …
biomimetic principles to create key aspects of living organs faithfully, including critical …
Auxetic cardiac patches with tunable mechanical and conductive properties toward treating myocardial infarction
M Kapnisi, C Mansfield, C Marijon… - Advanced functional …, 2018 - Wiley Online Library
An auxetic conductive cardiac patch (AuxCP) for the treatment of myocardial infarction (MI) is
introduced. The auxetic design gives the patch a negative Poisson's ratio, providing it with …
introduced. The auxetic design gives the patch a negative Poisson's ratio, providing it with …
Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model
Abstract Three-dimensional (3D) cell cultures represent fundamental tools for the
comprehension of cellular phenomena both in normal and in pathological conditions. In …
comprehension of cellular phenomena both in normal and in pathological conditions. In …
Sequentially-crosslinked bioactive hydrogels as nano-patterned substrates with customizable stiffness and degradation for corneal tissue engineering applications
M Rizwan, GSL Peh, HP Ang, NC Lwin, K Adnan… - Biomaterials, 2017 - Elsevier
Naturally-bioactive hydrogels like gelatin provide favorable properties for tissue-engineering
but lack sufficient mechanical strength for use as implantable tissue engineering substrates …
but lack sufficient mechanical strength for use as implantable tissue engineering substrates …
Advancement of sensor integrated organ-on-chip devices
GA Clarke, BX Hartse, AE Niaraki Asli, M Taghavimehr… - Sensors, 2021 - mdpi.com
Organ-on-chip devices have provided the pharmaceutical and tissue engineering worlds
much hope since they arrived and began to grow in sophistication. However, limitations for …
much hope since they arrived and began to grow in sophistication. However, limitations for …
Biohybrid 3D Printing of a Tissue‐Sensor Platform for Wireless, Real‐Time, and Continuous Monitoring of Drug‐Induced Cardiotoxicity
Drug‐induced cardiotoxicity is regarded as a major hurdle in the early stages of drug
development. Although there are various methods for preclinical cardiotoxicity tests, they …
development. Although there are various methods for preclinical cardiotoxicity tests, they …