Nets in fibrosis: Bridging innate immunity and tissue remodeling

X Ma, J Li, M Li, G Qi, L Wei, D Zhang - International Immunopharmacology, 2024 - Elsevier
Fibrosis, a complex pathological process characterized by excessive deposition of
extracellular matrix components, leads to tissue scarring and dysfunction. Emerging …

[HTML][HTML] The promotive effect of Caspase-11 overexpression in a rat model of chronic kidney disease and the therapeutic efficacy of exosome-delivered siRNA in …

J Tan, L Feng, ND Ragavan, OC Theam, X Li - … and Biophysical Research …, 2024 - Elsevier
This study investigates the role of Caspase-11 in Chronic Kidney Disease (CKD) and
examines the therapeutic potential of inhibiting Caspase-11 using exosome-mediated …

NINJ1-mediated macrophage plasma membrane rupture and neutrophil extracellular trap formation contribute to oxalate nephropathy

Y Lin, Y Yuan, K Ye, Z Chen, Y Wang… - Nephrology Dialysis …, 2024 - academic.oup.com
Background Oxalate nephropathy is characterized by calcium oxalate crystals deposition,
which triggers necrosis of renal tubular epithelial cells and initiates an inflammatory cascade …

GSDMD-dependent NET formation in hyperuricemic nephropathy

XY Han - Cellular and Molecular Life Sciences, 2024 - Springer
X.-Y. Han formation, research has shown that GSDMD-deficient mice are hypersensitive to
acute kidney injury [8]. An intricate role of GSDMD in inflammation, especially in kidney …