Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …

Located between vessels of the choriocapillaris and light-sensitive outer segments of the
photoreceptors, the retinal pigment epithelium (RPE) closely interacts with photoreceptors in …

Classic cadherins, which are known to be crucial for homotypic cell—cell adhesion, have
been found to be present not only in vertebrate but also in invertebrate species. Their three …

Although the pulmonary epithelia seem to be naturally permeable to a variety of peptides
and proteins, the mechanisms of absorption are poorly understood. Possible mechanisms of …

Cell polarity is the ultimate reflection of complex mechanisms that establish and maintain
functionally specialized domains in the plasma membrane and cytoplasm. The spatial …

Cadherins comprise a family of calcium‐dependent glycoproteins that function in mediating
cell‐cell adhesion in virtually all solid tissues of multicellular organisms. In epithelial cells, E …

▪ Abstract Adherens junctions are specialized forms of cadherin-based adhesive contacts
important for tissue organization in developing and adult organisms. Cadherins form protein …

In this review, we define the two major tissue types, epithelium and mesenchyme, and we
describe the transformations (transdifferentiations) of epithelium to mesenchyme (EMT) and …

Cadherin cell–cell adhesion molecules form membrane-spanning molecular complexes that
couple homophilic binding by the cadherin ectodomain to the actin cytoskeleton. A …

A spheroid is an in vitro multicellular aggregate that provides a microenvironment
resembling that of normal tissue in vivo. Although cell adhesion molecules such as integrins …