The glycosylation in SARS-CoV-2 and its receptor ACE2

Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

Coronavirus envelope protein: current knowledge

D Schoeman, BC Fielding - Virology journal, 2019 - Springer
Abstract Background Coronaviruses (CoVs) primarily cause enzootic infections in birds and
mammals but, in the last few decades, have shown to be capable of infecting humans as …

Cell entry mechanisms of SARS-CoV-2

J Shang, Y Wan, C Luo, G Ye, Q Geng… - Proceedings of the …, 2020 - National Acad Sciences
A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) is
causing the global coronavirus disease 2019 (COVID-19) pandemic. Understanding how …

Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition

OC Grant, D Montgomery, K Ito, RJ Woods - Scientific reports, 2020 - nature.com
Here we have generated 3D structures of glycoforms of the spike (S) glycoprotein from
SARS-CoV-2, based on reported 3D structures and glycomics data for the protein produced …

Structural features of coronavirus SARS-CoV-2 spike protein: Targets for vaccination

A Sternberg, C Naujokat - Life sciences, 2020 - Elsevier
Various human pathogenic viruses employ envelope glycoproteins for host cell receptor
recognition and binding, membrane fusion and viral entry. The spike (S) glycoprotein of …

Can SARS-CoV-2 virus use multiple receptors to enter host cells?

LK Gadanec, KR McSweeney, T Qaradakhi… - International journal of …, 2021 - mdpi.com
The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …

Characterization of the SARS‐CoV‐2 E protein: sequence, structure, viroporin, and inhibitors

Y Cao, R Yang, I Lee, W Zhang, J Sun, W Wang… - Protein …, 2021 - Wiley Online Library
The COVID‐19 epidemic is one of the most influential epidemics in history. Understanding
the impact of coronaviruses (CoVs) on host cells is very important for disease treatment. The …

Towards treatment planning of COVID-19: Rationale and hypothesis for the use of multiple immunosuppressive agents: Anti-antibodies, immunoglobulins, and …

A Saghazadeh, N Rezaei - International immunopharmacology, 2020 - Elsevier
The novel coronavirus, SARS-CoV2, can cause a potentially fatal disease, COVID-19, in
humans. Here, we will provide an overview of therapeutic options for COVID-19. Plasma …

[HTML][HTML] An evidence based perspective on mRNA-SARS-CoV-2 vaccine development

F Wang, RM Kream, GB Stefano - Medical science monitor …, 2020 - ncbi.nlm.nih.gov
The first outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, Hubei Province …

An overview of influenza viruses and vaccines

RF Nuwarda, AA Alharbi, V Kayser - Vaccines, 2021 - mdpi.com
Influenza remains one of the major public health concerns because it causes annual
epidemics and can potentially instigate a global pandemic. Numerous countermeasures …