Targeting tyrosine kinases in ovarian cancer: small molecule inhibitor and monoclonal antibody, where are we now?

A Rendell, I Thomas-Bland, L McCuish, C Taylor… - Biomedicines, 2022 - mdpi.com
Ovarian cancer is one of the most lethal gynaecological malignancies worldwide. Despite
high success rates following first time treatment, this heterogenous disease is prone to …

Deregulated metabolic pathways in ovarian cancer: cause and consequence

R Murali, V Balasubramaniam, S Srinivas, S Sundaram… - Metabolites, 2023 - mdpi.com
Ovarian cancers are tumors that originate from the different cells of the ovary and account for
almost 4% of all the cancers in women globally. More than 30 types of tumors have been …

Fourier-transform infrared spectroscopy coupled with a classification machine for the analysis of blood plasma or serum: a novel diagnostic approach for ovarian …

K Gajjar, J Trevisan, G Owens, PJ Keating, NJ Wood… - Analyst, 2013 - pubs.rsc.org
Currently available screening tests do not deliver the required sensitivity and specificity for
accurate diagnosis of ovarian or endometrial cancer. Infrared (IR) spectroscopy of blood …

Combining vascular normalization with an oncolytic virus enhances immunotherapy in a preclinical model of advanced-stage ovarian cancer

K Matuszewska, LA Santry, JP van Vloten… - Clinical Cancer …, 2019 - AACR
Purpose: Intravenous delivery of oncolytic viruses often leads to tumor vascular shutdown,
resulting in decreased tumor perfusion and elevated tumor hypoxia. We hypothesized that …

Trends in the incidence of ovarian cancer in sub‐Saharan Africa

M Gizaw, DM Parkin, O Stöter, A Korir… - … Journal of Cancer, 2023 - Wiley Online Library
Ovarian cancer (OC) is one of the commonest cancers of women in sub‐Saharan Africa
(SSA), although to date no data have been available on time trends in incidence to better …

Vibrational biospectroscopy coupled with multivariate analysis extracts potentially diagnostic features in blood plasma/serum of ovarian cancer patients

GL Owens, K Gajjar, J Trevisan… - Journal of …, 2014 - Wiley Online Library
Despite numerous advances in “omics” research, early detection of ovarian cancer still
remains a challenge. The aim of this study was to determine whether attenuated total …

[HTML][HTML] Serous ovarian cancer caused by exposure to asbestos and fibrous talc in cosmetic talc powders—a case series

JE Steffen, T Tran, M Yimam, KM Clancy… - … of Occupational and …, 2020 - journals.lww.com
Funding: Plaintiffs' attorneys in litigation against Johnson & Johnson (Ingham et al vs
Johnson & Johnson et al) paid for tissue analysis for talc and asbestos in patient tissues …

Mechanical characterization of 3D ovarian cancer nodules using Brillouin confocal microscopy

C Conrad, KM Gray, KM Stroka, I Rizvi… - Cellular and molecular …, 2019 - Springer
Introduction The mechanical interaction between cells and their microenvironment is
emerging as an important determinant of cancer progression and sensitivity to treatment …

Awareness and knowledge of ovarian cancer symptoms and risk factors: a survey of Jordanian women

M Freij, M Al Qadire, M Khadra… - Clinical Nursing …, 2018 - journals.sagepub.com
Ovarian cancer accounts for 3% of all female cancers and has a high mortality rate among
gynecological malignancies. Early diagnosis carries a high survival rate of 93%. So, this …

[HTML][HTML] Ovarian cancer: molecular classification and targeted therapy

F Ravindran, B Choudhary - Ovarian Cancer-Updates in Tumour …, 2021 - intechopen.com
Ovarian cancer is the deadliest gynecological cancer among women with an overall 5-year
survival rate below 50% due to its asymptomatic nature, diagnosis at advanced stages, and …