Abstract Familial Mediterranean fever (FMF)(OMIM# 249100) is the most common hereditary
autoinflammatory disease in the world. FMF is caused by gain of function mutations of MEFV …

Multiple myeloma remains an incurable disease with the usual disease course requiring
induction therapy, autologous stem cell transplantation for eligible patients, and long-term …

Familial Mediterranean fever (FMF) is the most frequent monogenic autoinflammatory
disease, and it is characterized by recurrent attacks of fever and polyserositis. The disease is …

OBJECTIVES: To analyze whether there were clinical differences between genetically
positive and negative patients fulfilling periodic fever, aphthous stomatitis, pharyngitis, and …

Background The Q705K polymorphism in NLRP3 has been implicated in several chronic
inflammatory diseases. In this study we determine the functional role of this commonly …

Familial Mediterranean fever (FMF) is an inherited autosomal recessive disorder, ethnically
restricted and commonly found among individuals of Mediterranean descent, caused by …

Background and aim Familial Mediterranean fever (FMF) is an autoinflammatory disease
caused by mutations of the MEFV gene. We analyse the impact of ethnic, environmental and …

Objective To develop widely accepted international severity score for children and adult
patients with familial Mediterranean fever (FMF) that can be easily applied, in research and …

Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory
disease manifesting with phenotypic heterogeneity. The phenotype–genotype correlation is …

Objectives Autoinflammatory diseases cause systemic inflammation that can result in
damage to multiple organs. A validated instrument is essential to quantify damage in …