The family of NF-κB transcription factors plays a key role in diverse biological processes,
such as inflammatory and immune responses, cell survival and tumor development. Beyond …

In this mini-review, we discuss the role of NF-κB, a proinflammatory transcription factor, in
the expression of genes involved in inflammation, proliferation, and apoptosis pathways …

K-Ras dependent non-small cell lung cancer (NSCLC) cells are 'addicted'to basal
autophagy that reprograms cellular metabolism in a lysosomal-sensitive manner. Here we …

Background Monocytic myeloid-derived suppressor cells (MDSCs), particularly the S100A9+
subset, has been shown initial clinical relevance. However, its role in EGFR-mutated lung …

A growing number of studies has shed light on the role of the NF-κΒ in non-small-cell lung
cancer (NSCLC). To address the significance of major effectors of the NF-κΒ alternative …

Emerging evidence has demonstrated that high-temperature requirement protein A1 (HtrA1)
appears to be involved in several important biological processes in mammals such as …

While many studies have demonstrated that canonical NF-κB signaling is a central pathway
in lung tumorigenesis, the role of non-canonical NF-κB signaling in lung cancer remains …

Nuclear factor (NF)-κB signalling is required for lung adenocarcinoma development in mice,
and both of its subunits Rel A and Rel B were independently reported to be highly …

Background Lung cancer is a major public health issue in most countries, including China.
The expression of RelB is associated with poor prognosis in diverse cancers. However …

RATIONALE: Clusterin expression may change in various human malignancies, including
lung cancer. Patients with resectable non-small cell lung cancer (NSCLC), including …