Biocatalysis has revolutionized chemical synthesis, providing sustainable methods for
preparing various organic molecules. In enzyme-mediated organic synthesis, most reactions …

Excited (triplet) states offer a myriad of attractive synthetic pathways, including
cycloadditions, selective homolytic bond cleavages and strain-release chemistry …

In recent years, powerful genetic code reprogramming methods have emerged that allow
new functional components to be embedded into proteins as noncanonical amino acid …

State-of-the-art non-natural photoenzymatic catalysis typically relies on either ultraviolet light
activation or the formation of electron donor–acceptor complexes. Inspired by nature, herein …

Strategies for achieving asymmetric catalysis with azaarenes have traditionally fallen short
of accomplishing remote stereocontrol, which would greatly enhance accessibility to distinct …

Enzymes are recognized as exceptional catalysts for achieving high stereoselectivities,–, but
their ability to control the reactivity and stereoinduction of free radicals lags behind that of …

Catalysis has a central role in organic synthetic methodology, especially in stereoselective
reactions. In many reactions, enantioselectivity is made possible through the use of chiral …

The enantioselective reduction of enamides is an efficient and atom-economical way to
construct chiral amine motifs. In contrast to transition-metal complex based asymmetric …

Designing efficient enzymes is a formidable challenge at the forefront of modern
biocatalysis. Here, we review recent developments in the field and illustrate how the …

Radical cations show a unique reactivity that is fundamentally different from that of
conventional cations and have thus attracted considerable attention as alternative cationic …