Vitamin A, a generic designation for an array of organic molecules that includes retinal,
retinol and retinoic acid, is an essential nutrient needed in a wide array of aspects including …

Chemokine–chemokine receptor interactions are important to hematopoiesis and immune
cell function, two highly interactive processes. Recent studies have clarified the role of …

Regulatory T (Treg) cells facilitate maternal immune tolerance of the semiallogeneic
conceptus in early pregnancy, but the origin and regulation of these cells at embryo …

The main function of the immune system is to fight off potential infections, but also to
maintain its activity below a level that would trigger self-reactivity. Regulatory T cells (Tregs) …

Bladder cancer presents a significant challenge for patient treatment and prognostic health
due to its high recurrence and metastasis. Nanoparticle-based photothermal therapy offers a …

STUDY QUESTION What is the mechanism of Tim-3+ regulatory T (Treg)-cell accumulation
in the decidua during early pregnancy and is its disruption associated with recurrent …

Results We found five populations of macrophages: cells with a single reaction: only for
CCR7+ or CD163+, a double reaction (CCR7+ CD163+), cells with a stronger CD163 …

Chemokine-dependent localization of specific B cell subsets within the immune
microarchitecture is essential to ensure successful cognate interactions. Although cognate …

Lymphocyte migration is at the heart of chronic inflammatory ailments, including
inflammatory bowel disease (IBD). Whereas naïve lymphocytes migrate to all secondary …

Despite major advances in the treatment of rheumatoid arthritis (RA) led by the success of
biologic therapies, the lack of response to therapy in a proportion of patients, as well as …