Highlights•Multiomics analyses to study peripheral artery disease and therapeutic gene
targets.•Gene therapy strategies targeting pathogenic hubs to treat peripheral artery …

This Commentary highlights the under-recognized prevalence and heavy burden of
peripheral artery disease (PAD) and its important role as a harbinger of complications of …

Background: There are limited data supporting or opposing the use of infrapopliteal
peripheral vascular interventions (PVI) for the treatment of claudication. Objectives: We …

Objective This study explores the association of serum 25-hydroxyvitamin D3 (25 (OH) D3)
levels with carotid artery intima-media thickness (CIMT), and the presence of carotid …

Objective Infrapopliteal peripheral vascular interventions (PVIs) for claudication are still
performed in the USA. This study aimed to evaluate whether infrapopliteal PVI is associated …

Background Diabetes mellitus (DM) is a major risk factor for peripheral artery disease. The
association of DM with major adverse limb events (MALE) after lower extremity …

Introduction Patients with peripheral arterial disease (PAD) frequently require
reinterventions after lower-extremity revascularization (LER) to maintain perfusion. Current …

Introduction Partial calcanectomy (PC) can be performed to treat chronic heel ulcers in
patients with calcaneal osteomyelitis. Patients undergoing PC often have multiple …

Background End-stage kidney disease (ESKD) is a risk factor for peripheral arterial disease
and major adverse limb events following infra-inguinal bypass. Despite comprising an …

Background Percutaneous deep venous arterialization (pDVA) has emerged as a new
modality for limb salvage in patients with chronic limb threatening ischemia (CLTI) and no …