Current concepts on the reno-protective effects of phosphodiesterase 5 inhibitors in acute kidney injury: systematic search and review

G Georgiadis, IE Zisis, AO Docea, K Tsarouhas… - Journal of clinical …, 2020 - mdpi.com
Acute kidney injury (AKI) is associated with increased morbidity, prolonged hospitalization,
and mortality, especially in high risk patients. Phosphodiesterase 5 inhibitors (PDE5Is) …

Cyclic nucleotide phosphodiesterase inhibition as a potential therapeutic target in renal ischemia reperfusion injury

K Thapa, TG Singh, A Kaur - Life sciences, 2021 - Elsevier
Abstract Aims Ischemia/reperfusion (I/R) occurs in renal artery stenosis, partial nephrectomy
and most commonly during kidney transplantation. It brings serious consequences such as …

Use of Mannitol for ischemia reperfusion injury in kidney transplant and partial nephrectomies—review of literature

JA Lugo-Baruqui, R Ayyathurai, A Sriram… - Current Urology …, 2019 - Springer
Abstract Purpose of Review Few procedures involve the ischemia-reperfusion injury to
organs purposely. Two clear examples in urologic surgery consist on kidney transplantation …

Reno-protective effects of Phosphodiesterase 5 inhibitors

ER Coskuner, B Ozkan - Clinical and experimental nephrology, 2021 - Springer
The kidneys are vital organs that play an important role in removing waste materials from the
blood, electrolyte balance, blood pressure regulation, and red blood cell genesis. Kidney …

[HTML][HTML] Protective effect of udenafil against ischemia reperfusion injury due to testicular torsion/detorsion in rat model

Z Sertkaya, O Koca, M Ozturk, M Akyuz… - The Eurasian Journal …, 2020 - ncbi.nlm.nih.gov
Objective Testicular torsion causes migration of neutrophils to the ischemic region and
formation of free oxygen radicals that have a critical effect on ischemic reperfusion (I/R) …

[HTML][HTML] Carbon monoxide–releasing molecule-3: Amelioration of renal ischemia reperfusion injury in a rat model

DK Kim, SJ Shin, J Lee, SY Park, YT Kim… - … and Clinical Urology, 2020 - ncbi.nlm.nih.gov
Purpose Despite the role of carbon monoxide in ameliorating ischemia-reperfusion injury
(IRI), its use in the clinical setting is restricted owing to its toxicity. Herein, we investigated the …

[PDF][PDF] The efficiency of oxerutin on apoptosis and kidney function in rats with renal ischemia reperfusion injury

A Güzel, A Özorak, T Oksay, SA Öztürk… - Turkish Journal of …, 2022 - jag.journalagent.com
ABSTRACT BACKGROUND: Background: Renal ischemia-reperfusion injury (RIRI) is the
most frequent cause of acute renal failure in clinical conditions such as trauma and shock as …

Renoprotective effects of tadalafil on ischemia-reperfusion injury during partial nephrectomy in an animal model

YS Ha, ES Yoo, BH Yoon, M Jeon, TG Kwon, BS Kim… - 2024 - researchsquare.com
Background: The safe time for partial nephrectomy is reported as 25 min for warm ischemia.
However, even in the case of arterial ligation within 25 min, acute renal injury occurs, which …

Examining mannitol use in kidney cancer surgery: a cautionary tale of extrapolated surgical data

SM Nair, NE Power, JA Coleman - European urology focus, 2019 - Elsevier
Maintaining adequate renal function is critical to physiologic homeostasis and important to
survival [1]. A link is recognized between renal dysfunction and overall medical comorbidity …

Chrysin or mannitol for treatment of acute kidney injury: Evidence for pharmacokinetic interaction

HMI Abdallah, SA El Awdan, SA El-Marasy… - Journal of Applied …, 2021 - japsonline.com
Acute kidney injury (AKI) is a heterogeneous disorder that is associated with high percent
morbidity and mortality especially in hospitalized patients. Seeking new drugs that have …