Indole diterpenoid natural products as the inspiration for new synthetic methods and strategies

MA Corsello, J Kim, NK Garg - Chemical science, 2017 - pubs.rsc.org
Indole terpenoids comprise a large class of natural products with diverse structural
topologies and a broad range of biological activities. Accordingly, indole terpenoids have …

Research status of indole-modified natural products

SF Duan, L Song, HY Guo, H Deng, X Huang… - RSC Medicinal …, 2023 - pubs.rsc.org
Indole is a heterocyclic compound formed by the fusion of a benzene ring and pyrrole ring,
which has rich biological activity. Many indole-containing compounds have been sold on the …

Total synthesis of hybridaphniphylline B

W Zhang, M Ding, J Li, Z Guo, M Lu… - Journal of the …, 2018 - ACS Publications
Hybridaphniphylline B (1) is a Daphniphyllum alkaloid possessing 11 rings and 19
stereocenters. Here we report the first total synthesis of 1 featuring a late-stage …

Total synthesis of rubriflordilactone B

P Yang, M Yao, J Li, Y Li, A Li - … Chemie International Edition, 2016 - Wiley Online Library
Taking advantage of a 6π electrocyclization–aromatization strategy, we accomplished the
first and asymmetric total synthesis of rubriflordilactone B, a heptacyclic Schisandraceae …

Total synthesis and stereochemical assignment of delavatine A: Rh-catalyzed asymmetric hydrogenation of indene-type tetrasubstituted olefins and kinetic resolution …

Z Zhang, J Wang, J Li, F Yang, G Liu… - Journal of the …, 2017 - ACS Publications
Delavatine A (1) is a structurally unusual isoquinoline alkaloid isolated from Incarvillea
delavayi. The first and gram-scale total synthesis of 1 was accomplished in 13 steps (the …

Chiral spiro phosphoric acid-catalyzed friedel–crafts conjugate addition/enantioselective protonation reactions

YP Li, ZQ Li, B Zhou, ML Li, XS Xue, SF Zhu… - Acs …, 2019 - ACS Publications
Asymmetric Friedel–Crafts conjugate addition reactions that generate an α-chiral center are
challenging because the configuration-determining step is a proton-transfer reaction of a …

[图书][B] Progress in the chemistry of organic natural products

AD Kinghorn, H Falk, S Gibbons, Y Asakawa, JK Liu… - 2021 - Springer
Termites (Isoptera), which are a suborder of the cockroaches, are the oldest eusocial insects
[1–3]. It is assumed that they diverged from the Cryptocercoidae, woodfeeding cockroaches …

Total synthesis of paspaline A and emindole PB enabled by computational augmentation of a transform-guided retrosynthetic strategy

DE Kim, JE Zweig, TR Newhouse - Journal of the American …, 2019 - ACS Publications
We report the total syntheses of two indole diterpenoid natural products, paspaline A and
emindole PB. Paspaline A is synthesized in a 9-step sequence from commercially available …

Asymmetric total syntheses of aspidodasycarpine, lonicerine, and the proposed structure of lanciferine

Y Li, S Zhu, J Li, A Li - Journal of the American Chemical Society, 2016 - ACS Publications
Aspidodasycarpine and lonicerine are a pair of epimeric aspidophylline-type alkaloids
bearing vicinal quaternary C7 and C16. The first and enantioselective total syntheses of …

Total synthesis of epoxyeujindole A

Z Lu, H Li, M Bian, A Li - Journal of the American Chemical …, 2015 - ACS Publications
The total synthesis of epoxyeujindole A, a structurally unusual indole diterpenoid isolated
from Eupenicillium javanicum, has been accomplished for the first time. The synthesis …