Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

Background Excessive blood loss is a significant risk of myomectomy with the potential need
for hysterectomy. Objective To study the effectiveness of preoperative misoprostol compared …

Objective: This study offered an updated meta-analysis of randomized controlled trials
(RCTs) that assessed preoperative misoprostol compared to control (matched placebos or …

Background: Despite using a tourniquet to reduce bleeding during abdominal myomectomy,
the procedure is still complicated by significant intraoperative bleeding. Aim: To determine …

Background: Uterine leiomyomas are the commonest benign tumours in women, which are
estrogen-dependent and grow during the reproductive life. Standard treatment for …

Background: Myomectomy is a common gynecological procedure that can be approached,
depending on fibroid location, hysteroscopically or abdominally. The impact of excessive …

Background: Open myomectomy remains the main option has been shown to have
satisfactory results as regard fertility preservation and symptom resolution, especially when …

Background: Misoprostol is a synthetic version of prostaglandin E1, unlike its naturally
occurring counterpart. Prostaglandins enhance the contractions of the myometrium, resulting …

Objective: To compare intraoperative blood loss in patients undergoing abdominal
myomectomy with and without a single preoperative dose of per vaginal misoprostol …

Aim: The aim of the study is to compare the efficacy and safety of rectal Misoprostol versus IV
Tranexamic acid (TXA) in reducing intraoperative blood loss during open myomectomy …