Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …

The peritoneal cavity is a fluid filled space that holds most of the abdominal organs,
including the omentum, a visceral adipose tissue that contains milky spots or clusters of …

Efficient generation of germinal center (GC) responses requires directed movement of B
cells between distinct microenvironments underpinned by specialized B cell–interacting …

Peritoneal fibrosis is characterized by abnormal production of extracellular matrix proteins
leading to progressive thickening of the submesothelial compact zone of the peritoneal …

Fibroblastic reticular cells (FRCs) are a crucial part of the stromal cell infrastructure of
secondary lymphoid organs (SLOs). Lymphoid organ fibroblasts form specialized niches for …

The failure to generate enduring humoral immunity after vaccination is a hallmark of
advancing age. This can be attributed to a reduction in the germinal center (GC) response …

Lymphoid organs guarantee productive immune cell interactions through the establishment
of distinct microenvironmental niches that are built by fibroblastic reticular cells (FRC). These …

The omentum is a visceral adipose tissue rich in fat-associated lymphoid clusters (FALCs)
that collects peritoneal contaminants and provides a first layer of immunological defense …

Aims Newborn mice and humans display transient cardiac regenerative potential that rapidly
declines postnatally. Patients who survive a myocardial infarction (MI) often develop chronic …

Fibroblastic reticular cells (FRCs) are specialized fibroblasts of secondary lymphoid organs
that provide the structural foundation of the tissue. Moreover, FRCs guide immune cells to …