Human blood monocytes are heterogeneous and conventionally subdivided into two
subsets based on CD16 expression. Recently, the official nomenclature subdivides …

T cells are required for immune surveillance of the central nervous system (CNS); however,
they can also induce severe immunopathology in the context of both viral infections and …

Human immunodeficiency virus (HIV)‐associated neurocognitive disorders (HANDs) remain
among the most common disorders in people infected with HIV, even in an era when potent …

Hematopoietic stem cells (HSC) can be harmed by disease, chemotherapy, radiation, and
normal aging. We show in this study that damage also occurs in mice repeatedly treated with …

Viral infections are a major cause of human disease. Although most viruses replicate in
peripheral tissues, some have developed unique strategies to move into the nervous …

Globally, human immunodeficiency virus type 1 (HIV-1) infection is a major health burden for
which successful therapeutic options are still being investigated. Challenges facing current …

HIV can infect the brain and impair central nervous system (CNS) function. Combination
antiretroviral therapy (cART) has not eradicated CNS complications. HIV-associated …

Thirty-five years after the identification of HIV-1 as the causative agent of AIDS, we are still in
search of vaccines and treatments to eradicate this devastating infectious disease. Progress …

HIV is a devastating human pathogen that causes serious immunological diseases in
humans around the world. The virus is able to remain latent in an infected host for many …

Treatment of HIV‐infected patients with highly active antiretroviral therapy (HAART) usually
results in diminished viral replication, increasing CD4+ cell counts, a reversal of most …