Evolution of the immune system in humans from infancy to old age

AK Simon, GA Hollander… - Proceedings of the …, 2015 - royalsocietypublishing.org
This article reviews the development of the immune response through neonatal, infant and
adult life, including pregnancy, ending with the decline in old age. A picture emerges of a …

Ontogeny of early life immunity

DJ Dowling, O Levy - Trends in immunology, 2014 - cell.com
The human immune system comprises cellular and molecular components designed to
coordinately prevent infection while avoiding potentially harmful inflammation and …

Development of child immunity in the context of COVID-19 pandemic

M Kloc, RM Ghobrial, E Kuchar, S Lewicki, JZ Kubiak - Clinical Immunology, 2020 - Elsevier
Children, because of having an immature immune system, are usually more prone than the
adults to the microbial infections and have more severe symptoms, which is especially true …

[HTML][HTML] Pathogenesis of necrotizing enterocolitis: modeling the innate immune response

SM Tanner, TF Berryhill, JL Ellenburg, T Jilling… - The American journal of …, 2015 - Elsevier
Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in premature
infants. The pathophysiology is likely secondary to innate immune responses to intestinal …

The importance of human milk for immunity in preterm infants

ED Lewis, C Richard, BM Larsen… - Clinics in …, 2017 - perinatology.theclinics.com
The Importance of Human Milk for Immunity in Preterm Infants - Clinics in Perinatology Skip to
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Pathophysiology of necrotizing enterocolitis: an update

C Bazacliu, J Neu - Current pediatric reviews, 2019 - ingentaconnect.com
NEC is a devastating disease that, once present, is very difficult to treat. In the absence of an
etiologic treatment, preventive measures are required. Advances in decoding the …

Immunomodulation to prevent or treat neonatal sepsis: past, present, and future

SS Schüller, BW Kramer, E Villamor, A Spittler… - Frontiers in …, 2018 - frontiersin.org
Despite continued advances in neonatal medicine, sepsis remains a leading cause of death
worldwide in neonatal intensive care units. The clinical presentation of sepsis in neonates …

[HTML][HTML] Breastfeeding and the developmental origins of mucosal immunity: how human milk shapes the innate and adaptive mucosal immune systems

B Dawod, JS Marshall, MB Azad - Current Opinion in …, 2021 - journals.lww.com
Breastfeeding and the developmental origins of mucosal immun... : Current Opinion in
Gastroenterology Breastfeeding and the developmental origins of mucosal immunity: how …

Role of early life immune regulation in asthma development

J Krusche, S Basse, B Schaub - Seminars in immunopathology, 2020 - Springer
Abstract Development of childhood asthma is complex with a strong interaction of genetic,
epigenetic, and environmental factors. Ultimately, it is critical how the immune system of a …

The role of immunity in the pathogenesis of SARS-CoV-2 infection and in the protection generated by COVID-19 vaccines in different age groups

ZA Abdulla, SM Al-Bashir, H Alzoubi, NS Al-Salih… - Pathogens, 2023 - mdpi.com
This study aims to review the available data regarding the central role of immunity in
combating SARS-CoV-2 infection and in the generation of protection by vaccination against …