RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …

RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …

Mutations causing amyotrophic lateral sclerosis (ALS) often affect the condensation
properties of RNA-binding proteins (RBPs). However, the role of RBP condensation in the …

Proteins and RNA functionally and physically intersect in multiple biological processes,
however, currently no universal method is available to purify protein-RNA complexes. Here …

The maternal-to-zygotic transition (MZT) is a conserved and fundamental process during
which the maternal environment is converted to an environment of embryonic-driven …

RNA binding proteins (RBPs) regulate all aspects in the life cycle of RNA molecules. To
elucidate the elements that guide RNA specificity, regulatory mechanisms, and functions of …

Discovery of interaction sites between RNA-binding proteins (RBPs) and their RNA targets
plays a critical role in enabling our understanding of how these RBPs control RNA …

Functions of many long noncoding RNAs (lncRNAs) depend on their ability to interact with
multiple copies of specific RNA-binding proteins (RBPs). Here, we devised a workflow …

Long mammalian introns make it challenging for the RNA processing machinery to identify
exons accurately. We find that LINE-derived sequences (LINEs) contribute to this selection …

The iCLIP and eCLIP techniques facilitate the detection of protein–RNA interaction sites at
high resolution, based on diagnostic events at crosslink sites. However, previous methods …