Recombinant BCG: innovations on an old vaccine. Scope of BCG strains and strategies to improve long-lasting memory
AC da Costa, SV Nogueira, A Kipnis… - Frontiers in …, 2014 - frontiersin.org
Bacille Calmette–Guérin (BCG), an attenuated vaccine derived from Mycobacterium bovis, is
the current vaccine of choice against tuberculosis (TB). Despite its protection against active …
the current vaccine of choice against tuberculosis (TB). Despite its protection against active …
Applications of bacillus Calmette–Guerin and recombinant bacillus Calmette–Guerin in vaccine development and tumor immunotherapy
Y Zheng, YW Naguib, Y Dong, Y Shi… - Expert review of …, 2015 - Taylor & Francis
Bacillus Calmette–Guerin (BCG) vaccines are attenuated live strains of Mycobacterium
bovis and are among the most widely used vaccines in the world. BCG is proven to be …
bovis and are among the most widely used vaccines in the world. BCG is proven to be …
Design, synthesis and biological evaluation of imidazo [2, 1-b] thiazole and benzo [d] imidazo [2, 1-b] thiazole derivatives as Mycobacterium tuberculosis pantothenate …
In the present study, we have designed imidazo [2, 1-b] thiazole and benzo [d] imidazo [2, 1-
b] thiazole derivatives from earlier reported imidazo [1, 2-a] pyridine based Mycobacterium …
b] thiazole derivatives from earlier reported imidazo [1, 2-a] pyridine based Mycobacterium …
PPE57 induces activation of macrophages and drives Th1-type immune responses through TLR2
Y Xu, E Yang, Q Huang, W Ni, C Kong, G Liu… - Journal of molecular …, 2015 - Springer
Proline-glutamic acid (PE) and proline-proline-glutamic acid (PPE) are related proteins
exclusive to Mycobacteria that play diverse roles in modulating critical innate immune …
exclusive to Mycobacteria that play diverse roles in modulating critical innate immune …
Chronic schistosomiasis suppresses HIV-specific responses to DNA-MVA and MVA-gp140 Env vaccine regimens despite antihelminthic treatment and increases …
GA Dzhivhuho, SA Rehrl, H Ndlovu… - PLoS …, 2018 - journals.plos.org
Future HIV vaccines are expected to induce effective Th1 cell-mediated and Env-specific
antibody responses that are necessary to offer protective immunity to HIV infection …
antibody responses that are necessary to offer protective immunity to HIV infection …
Auxotrophic Mycobacterium bovis BCG: Updates and Perspectives
Mycobacterium bovis BCG has been used for a century as the only licensed vaccine against
tuberculosis. Owing to its strong adjuvant properties, BCG has also been employed as an …
tuberculosis. Owing to its strong adjuvant properties, BCG has also been employed as an …
Balancing trained immunity with persistent immune activation and the risk of simian immunodeficiency virus infection in infant macaques vaccinated with attenuated …
K Jensen, MG dela Pena-Ponce… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Our goal is to develop a pediatric combination vaccine to protect the vulnerable infant
population against human immunodeficiency virus type 1 (HIV-1) and tuberculosis (TB) …
population against human immunodeficiency virus type 1 (HIV-1) and tuberculosis (TB) …
Prime–boost bacillus Calmette–Guérin vaccination with lentivirus‐vectored and DNA‐based vaccines expressing antigens Ag85B and Rv3425 improves protective …
Y Xu, E Yang, J Wang, R Li, G Li, G Liu, N Song… - …, 2014 - Wiley Online Library
To prevent the global spread of tuberculosis (TB), more effective vaccines and vaccination
strategies are urgently needed. As a result of the success of bacillus Calmette–Guérin (BCG) …
strategies are urgently needed. As a result of the success of bacillus Calmette–Guérin (BCG) …
Recombinant BCG vaccines: molecular features and their influence in the expression of foreign genes
TL Oliveira, C Rizzi, OA Dellagostin - Applied Microbiology and …, 2017 - Springer
Recombinant Mycobacterium bovis BCG vaccines (rBCG) were first developed in the 1990s
as a means of expressing antigens from multiple pathogens. This review examines the key …
as a means of expressing antigens from multiple pathogens. This review examines the key …
Advances and challenges in recombinant Mycobacterium bovis BCG-based HIV vaccine development: lessons learned
A Kilpeläinen, M Maya-Hoyos, N Saubí… - Expert Review of …, 2018 - Taylor & Francis
ABSTRACT Introduction: Human Immunodeficiency Virus/Acquired Immune Deficiency
Syndrome, tuberculosis, and malaria are responsible for most human deaths produced by …
Syndrome, tuberculosis, and malaria are responsible for most human deaths produced by …